Research Resource

Creative Biogene is committed to providing high quality products and services to help scientists around the world find solutions in biological research and drug discovery.

Research Areas

Emerging Therapeutic Potential of Adeno-Associated Virus-Mediated Gene Therapy in Liver Fibrosis

Liver fibrosis is a wound-healing response that results from various chronic damages. If the causes of damage are not removed or effective treatments are not given in a timely manner, it will progress to cirrhosis, even liver cancer. Currently, there are no specific medical therapies for liver fibrosis.

Advancing Genetic Engineering Harnessing the Power of Cre Recombinase AAV Particles

Genetic engineering has revolutionized various fields, from agriculture to medicine. One powerful tool in this domain is Cre recombinase, a naturally occurring enzyme that allows precise manipulation of genetic material.

Immune Receptor Stable Cell Lines: A Useful Tool in Aiding Anti-Tumor Novel Drugs Development

Immune checkpoints are the crucial regulators of immune system and play essential roles in maintaining self-tolerance, preventing autoimmune responses, and minimizing tissue damage by regulating the duration and intensity of the immune response.

Exosome Marker Lentiviral Particles Facilitate Exosome Tracking and Biodistribution Studies

Exosomes have many biological functions as short- and long distance nanocarriers for cell-to-cell communication. They allow the exchange of complex information between cells, and thereby modulate various processes such as homeostasis, immune response and angiogenesis, in both physiological and pathological conditions.

CAR-T Lentiviral Particles Helping to Establish an Efficient and Simple Platform for CAR-T Cell Expansion and Generation

Chimeric antigen receptor (CAR) T-cells represent a paradigm shift in cancer immunotherapy and a new milestone in the history of oncology. Among them, CD19-targeted drugs have achieved unprecedented success in the treatment of B-cell malignancies and were approved by the US FDA in 2017.

Adeno-Associated Viral Vectors in Neuroscience Research

Adeno-associated viral vectors (AAVs) are increasingly useful preclinical tools in neuroscience research studies for interrogating cellular and neurocircuit functions and mapping brain connectivity. Clinically, AAVs have for transformative research and therapeutics in the neurosciences.

Recombinase AAV Particles in Animal Experiments and Neurological Applications

The successful execution of neurobiology studies requires methods that are highly targetable, efficient, and precise. The arsenal of new sensors, actuators, recombinases, genes, RNA and base editing enzymes, and other genetically encoded tools for studying the nervous system is rapidly growing.

Application Prospects of Reporter Cell Lines

The reporter cell lines have shown great potential for cell tracing, drug development and gene function studies, etc. Creative Biogene offers reporter cell lines with high sensitivity and accurate localization, which have become a powerful tool of choice for researchers.

Application of Kinase Stable Cell Lines Detection of Secondary EGFR Mutations in Afatinib-Resistant BaF3 Cells

Kinases serve as key regulatory molecules for most cellular pathways, which are often associated with diseases: as causative agents for diseases, especially many cancers, or as targets for drug development.

AAV-HBV Transfection Mouse Model Efficient for Animal Experiments and HBV-Related Studies

Despite the availability of effective vaccination, hepatitis B virus (HBV) infection continues to be a major challenge worldwide. The exceptionally limited host spectrum of HBV has limited the research progress.

* For research use only. Not intended for any clinical use.

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