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Research Resource

Creative Biogene is committed to providing high quality products and services to help scientists around the world find solutions in biological research and drug discovery.

Research Areas

Clinical Prospects for Integrase-Deficient Lentivirus (IDLV)

Clinical Prospects for Integrase-Deficient Lentivirus (IDLV)

HIV-1 derived lentiviral vector is an efficient transporter for delivering desired genetic materials into the targeted cells among many viral vectors. Genetic material transduced by lentiviral vector is integrated into the cell genome to introduce new functions, repair defective cell metabolism, and stimulate certain cell functions.

Innovations in Gene Editing: Use of Cas9 Viral Particles in CRISPR Delivery

Innovations in Gene Editing: Use of Cas9 Viral Particles in CRISPR Delivery

To fully exploit the gene editing potential of CRISPR/Cas9, they must be efficiently introduced into target cells or tissues using appropriate vectors. Recombinant viral vectors have been developed using ability of viruses to transfer foreign genetic material into cells to deliver therapeutic genes to diseased tissues.

Potential Applications of Adenovirus-Mediated Gene Delivery in Gene and Cell-Based Therapies

Potential Applications of Adenovirus-Mediated Gene Delivery in Gene and Cell-Based Therapies

There has been a long-lasting interest in using viral vectors, especially adenoviral vectors, to deliver therapeutic genes for the past two decades. Among all currently available viral vectors, adenovirus is the most efficient gene delivery system in a broad range of cell and tissue types.

Harnessing Self-Amplifying RNA Viruses Revolutionizing RNA Vaccines

Harnessing Self-Amplifying RNA Viruses Revolutionizing RNA Vaccines

Creative Biogene introduces customers to the basic functions of self-replicating RNA viral vectors and describes various pre-clinical and clinical applications.

Overcoming Obstacles in Scaling Up Production of AAV-Based Gene Therapy

Overcoming Obstacles in Scaling Up Production of AAV-Based Gene Therapy

Creative Biogene presents to clients how successful applications in antibody production development translate into AAV to meet the challenges of scaling up their production.