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Protein Biology

Adaptor Protein Complex Interaction Map in Arabidopsis Identifies P34 as A Common Stability Regulator

Adaptor Protein Complex Interaction Map in Arabidopsis Identifies P34 as A Common Stability Regulator

Transport and distribution of biomolecules between plant cell endomembrane systems are essential for plant growth and development. Adaptor Protein (AP) is an evolutionarily very conserved class of complexes that are involved in the fine regulation of endosomal transport in plants.

Accelerating Drug Discovery with High-throughput Screening of Ion Channels

Accelerating Drug Discovery with High-throughput Screening of Ion Channels

Ion channels are a very important membrane protein family involved in a variety of fundamental physiological processes. Their malfunction causes a variety of human diseases. Therefore, ion channels represent a class of attractive drug targets and a class of important off-targets for in vitro pharmacological profiling.

Harnessing Ion Channels as Therapeutic Targets for Viral Infections

Harnessing Ion Channels as Therapeutic Targets for Viral Infections

Creative Biogene presented to the client about the potential biological mechanisms of mRNA vaccines and their applications in a number of infectious diseases and cancers.

Next-Generation Targeted Therapy Strategies: Design Optimization for ADCs and PDCs

Next-Generation Targeted Therapy Strategies: Design Optimization for ADCs and PDCs

Targeted therapy has shown significant potential in cancer treatment by directly targeting specific molecular markers on tumor cells, significantly improving treatment selectivity and efficacy.

Protein Lactylation: A New Link between Metabolism and Gene Expression Regulation

Protein Lactylation: A New Link between Metabolism and Gene Expression Regulation

In the long journey of life sciences research, scientists have continuously unveiled the mysteries of life activities. Recently, the discovery of a novel post-translational modification (PTM)—protein lactylation—has provided a new perspective on the connection between cellular metabolism and gene expression regulation.