Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Premade Virus Particles
Ready-to-Use | High Titer | Versatile Applications
Premade AAV, adenovirus, lentivirus particles, safe, stable, in stock.
Virus-Like Particles (VLPs)
Stable | Scalable | Customizable
Advanced VLPs for vaccine development (Chikungunya, Dengue, SARS-CoV-2), gene therapy (AAV1 & AAV9), and drug screening (SSTR2, CCR5).
Oligonucleotide Products
Precise | High Yield | Tailored Solutions
Accelerate your research with cost-effective LncRNA qPCR Array Technology.
RNA Interference Products
Targeted | Potent | High Specificity
Human Druggable Genome siRNA Library enables efficient drug target screening.
Recombinant Drug Target Proteins
Authentic | Versatile | Accelerated
Providing functional, high-purity recombinant proteins—including membrane proteins and nanodiscs—to overcome bottlenecks in drug screening and target validation.
Clones
Validated | Reliable | Comprehensive Collection
Ready-to-use clones for streamlined research and development.
Kits
Complete | Convenient | High Sensitivity
Chromogenic LAL Endotoxin Assay Kit ensures precise, FDA-compliant endotoxin quantification for biosafety testing.
Enzymes
Purified | Stable | Efficient
Powerful Tn5 Transposase for DNA insertion and random library construction.
Aptamers
Highly Specific | Robust | Versatile
Aptamers for key proteins like ACVR1A, Akt, EGFR, and VEGFR.
Adjuvants
Enhancing | Synergistic | Effective
Enhance immune responses with high-purity, potent CpG ODNs.
Laboratory Equipment
Innovative | Reliable | High-Precision
Effortlessly streamline DNA extraction with CB™ Magnetic-Nanoparticle Systems.
Stable Cell Line Generation
Reliable | Scalable | Customizable
Fast proposals, regular updates, and detailed reports; strict quality control, and contamination-free cells; knockout results in 4-6 weeks.
Target-based Drug Discovery Service
Innovative | Comprehensive | Efficient
Target identification, validation, and screening for drug discovery and therapeutic development.
Custom Viral Service
Versatile | High-Yield | Safe
Unbeatable pricing, fully customizable viral packaging services (covering 30,000+ human genes, 200+ mammals, 50+ protein tags).
Custom Antibody Service
Precise | Flexible | Efficient
End-to-end antibody development support, from target to validation, enabling clients to rapidly obtain application-ready antibodies.
Antibody-Drug Conjugation Service
Integrated | Controlled | Translational
Comprehensive solutions covering design, development, and validation to ensure conjugated drugs with consistent quality and clinical potential.
Protein Degrader Service
Efficient | High-Precision | Advanced Therapeutics
Harness the power of protein degraders for precise protein degradation, expanding druggable targets and enhancing therapeutic effectiveness for cutting-edge drug discovery.
Nucleotides Service
Accurate | Flexible | High-Quality
Custom synthesis of oligonucleotides, primers, and probes for gene editing, PCR, and RNA studies.
Custom RNA Service
Custom RNA ServicePrecise | Flexible | GMP-ReadyCustom
RNA design, synthesis, and manufacturing—covering mRNA, saRNA, circRNA, and RNAi. Fast turnaround, rigorous QC, and seamless transition from research to GMP production.
Custom Libraries Construction Service
Comprehensive | High-throughput | Accurate
Custom cDNA, genomic, and mutagenesis libraries for drug discovery, screening, and functional genomics.
Gene Editing Services
Precise | Efficient | Targeted
Gene editing solutions for gene editing, knockouts, knock-ins, and customized genetic modifications. Integrated multi-platform solutions for one-stop CRISPR sgRNA library synthesis and gene screening services
Microbe Genome Editing Service
Precise | Scalable | Customizable
Enhance microbial productivity with advanced genome editing using Rec-mediated recombination and CRISPR/Cas9 technologies.
Biosafety Testing Service
Reliable | Comprehensive | Regulated
Complete biosafety testing solutions for gene therapy, viral vectors, and biologics development.
Plant Genetic Modification Service
Advanced | Sustainable | Tailored
Genetic modification for crop improvement, biotechnology, and plant-based research solutions.
Plant-based Protein Production Service
Efficient | Scalable | Customizable
Plant-based protein expression systems for biopharmaceuticals, enzyme production, and research.
Aptamers Service
Innovative | Fast | Cost-Effective
Revolutionizing drug delivery and diagnostic development with next-generation high-throughput aptamer selection and synthesis technologies.
CGT Biosafety Testing
Comprehensive | Accurate | Regulatory-compliant
Internationally certified evaluation system for biologics, gene therapies, nucleic acid drugs, and vaccines.
Pandemic Detection Solutions
Rapid | Precise | Scalable
Balancing accuracy, accessibility, affordability, and rapid detection to safeguard public health and strengthen global response to infectious diseases.
cGMP Cell Line Development
Reliable | Scalable | Industry-leading
Stable expression over 15 generations with rapid cell line development in just 3 months.
Supports adherent and suspension cell lines, offering MCB, WCB, and PCB establishment.
GMP mRNA Production
Efficient | Scalable | Precise
Scalable mRNA production from milligrams to grams, with personalized process design for sequence optimization, cap selection, and nucleotide modifications, all in one service.
GMP Plasmid Production
High Quality | Scalable | Regulatory-compliant
Our plasmid production services span Non-GMP, GMP-Like, and GMP-Grade levels, with specialized options for linearized plasmids.
GMP Viral Vector Manufacturing
Scalable | High Yield | Quality-driven
Advanced platforms for AAV, adenovirus, lentivirus, and retrovirus production, with strict adherence to GMP guidelines and robust quality control.
AI-Driven Gene Editing and Therapy
Innovative | Precision | Transformative
AI-powered one-click design for customized CRISPR gene editing strategy development.
AI-Antibody Engineering Fusion
Next-Generation | Targeted | Efficient
AI and ML algorithms accelerate antibody screening and predict new structures, unlocking unprecedented possibilities in antibody engineering.
AI-Driven Enzyme Engineering
Smart | Efficient | Tailored
High-throughput enzyme activity testing with proprietary datasets and deep learning models for standardized and precise enzyme engineering design.
AI-Enhanced Small Molecule Screening
Predictive | Efficient | Insightful
Leverage AI to uncover hidden high-potential small molecules, prioritize leads intelligently, and reduce costly trial-and-error in early drug discovery.
AI-Driven Protein Degrader Drug Development
Innovative | Targeted | Accelerated
Use AI-guided design to optimize protein degraders, addressing design complexity and enhancing efficacy while shortening development timelines.
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Experiment Tags: Plasmid purification, Plasmid purification
Experiment Summary: Plasmids are small circular deoxyribonucleic acids (DNA) outside the chromosomes that replicate independently of chromosomal DNA. Although budding yeast and fission yeast can retain plasmids, the host of plasmids is almost always bacteria. This small circular DNA is widely used as a DNA vector in the fields of molecular biology, biochemistry, biotechnology, cell biology, etc.
Experiment Tags: Lentiviral Vectors, Stable Cell Line, Gene Expression, Viral Transduction, Cell Culture, Puromycin Selection, Virus Packaging, Mammalian Cells, Transgene Expression
Experiment Summary: This protocol details the generation of stable cell lines using lentiviral vectors. The method covers plasmid preparation, 293T cell transfection for viral packaging, PEG8000-based virus concentration, target cell infection, antibiotic selection parameters, and single-clone isolation. Includes MOI calculation guidance, troubleshooting for common challenges like low viral titer and poor infection efficiency, and validation strategies for ensuring stable transgene expression.
Experiment Tags: Bacterial Transformation, Bacterial Transformation Protocol, transformation, bacterial cells
Experiment Summary: Bacterial transformation is a fundamental process in molecular biology, enabling the introduction of foreign DNA into bacterial cells. Primarily used for the amplification and storage of plasmids, bacterial transformation is critical for cloning experiments.
Experiment Tags: CCK-8 assay, MTT assay, cell viability, drug treatment, IC50, absorbance measurement, cell seeding, aseptic technique, OD values, 96-well plate, biological assay, cytotoxicity, experimental protocol.
Experiment Summary: This protocol provides a step-by-step guide for performing CCK-8 and MTT cell viability assays, covering cell seeding, drug concentration settings, treatment duration, and absorbance measurement. It also includes important considerations for avoiding contamination, ensuring cell health, and interpreting results accurately, especially in high-throughput drug testing.
Experiment Tags: MPXV, A29L protein, B6R protein, M1R protein, HEK293T cells, Recombinant proteins, Protein purification, SDS-PAGE, Western blot, ELISA, Neutralization assay, Antibody titer
Experiment Summary: This protocol outlines the process for expressing, purifying, and analyzing MPXV antigens and assessing their immunogenicity, which is vital for vaccine research and development.
Experiment Tags: Dual-fluorescence, Flow Cytometry, Protein Analysis, Steady-State Protein Levels, eGFP mCherry, Transfection Efficiency, Cell Line Transfection, Protein Abundance
Experiment Summary: This protocol provides a powerful tool for studying protein expression levels under various cellular conditions, offering single-cell resolution and the ability to detect subtle differences that might be masked in bulk assays. Its versatility makes it applicable to a wide range of proteins and cellular contexts, contributing to our understanding of protein homeostasis and cellular biology.
Experiment Tags: CRISPR-Cas9, Gene Editing, C. elegans, sgRNA, Plasmid Construction Homologous Recombination, Genetic Screening.
Experiment Summary: This protocol outlines the process for performing CRISPR/Cas9-mediated genome modifications in C. elegans, including the design of specific sgRNA sequences, construction of Cas9-sgRNA plasmids, and preparation of injection mixtures.
Experiment Tags: 3D Tumorsphere Culture, Cancer Research, Matrigel Embedding, Tumor Tissue Culture, Cell Transduction, Cryopreservation, Cell Counting
Experiment Summary: This protocol outlines a comprehensive procedure for 3D tumorsphere cultivation, including cell transduction, 3D tumorsphere culture using Matrigel, primary tumorsphere culture from fresh tumor tissue, spheroid passaging, and cryopreservation. The protocol aims to replicate the 3D environment of solid tumors, aiding researchers in studying tumor biology and conducting drug screening.
Experiment Tags: Gene Editing, FLPe Recombinase, Cassette Exchange, AAVS1 Locus, Human Pluripotent Stem Cells
Experiment Summary: The protocol presents a unique approach to FLPe recombinase-mediated cassette exchange (RMCE) gene editing at the AAVS1 locus in human pluripotent stem cells (hPSCs) that is both rapid and efficient. This method makes it easier to generate highly reliable isogenic lines, which in turn makes transgenesis studies in hPSCs easier to conduct.
Experiment Tags: CRISPR/Cas9, Lentivirus, Gene Knockout, Cell Line Development
Experiment Summary: The protocol utilizes lentiviral vectors and a control system to regulate Cas9 activity, enabling the development of knockout cell lines. The development of a human muscle cell line that targets the gene serves as evidence of the protocol's effectiveness.
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