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RNA

MiRNAs: the Next Generation Drugs in Human Cancer

MiRNAs: the Next Generation Drugs in Human Cancer

In the past few years, therapeutic microRNA (miRNA) is some of the most important biopharmaceuticals that are in commercial space as future medicines. The discovery of therapeutic miRNA is considered one of the most exhilarating and significant therapeutic breakthroughs in pharmaceutical development.

Application of RNA-Seq Technology in Cancer Research

Application of RNA-Seq Technology in Cancer Research

Over the past few decades, RNA sequencing has significantly progressed, becoming a paramount approach for transcriptome profiling.

Prospects of RNAi in Cancer Therapy

Prospects of RNAi in Cancer Therapy

RNA interference (RNAi), a process that involves sequence-specific gene silencing, is an endogenous post-transcriptional regulation process that consists of non-coding RNAs like microRNAs (miRNAs), small interfering RNAs (siRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs)...

Exploring the Potential of CRISPRCas13-Mediated RNA Editing in Plants

Exploring the Potential of CRISPRCas13-Mediated RNA Editing in Plants

The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) system is widely used as a genome-editing tool in various organisms, including plants, to elucidate the fundamental understanding of gene function, disease diagnostics, and crop improvement.

Decoding the Synthesis of CircRNA: In Vitro Breakthroughs

Decoding the Synthesis of CircRNA: In Vitro Breakthroughs

Circular RNA (circRNA) is a unique type of noncoding RNA molecule. Compared with traditional linear RNA, circRNA is a covalently closed circle produced by a process called backsplicing. CircRNA is abundant in many cells and has rich functions in cells, such as acting as miRNA sponge, protein sponge, protein scaffold, and mRNA regulator.