Research Resource

Creative Biogene is committed to providing high quality products and services to help scientists around the world find solutions in biological research and drug discovery.

Research Areas

Gamma-Retroviral And Lentiviral Vector Production

Advantages And Opportunities of Plants And Plant Cell Cultures in Molecular Agriculture

Plants can express proteins that are toxic when expressed in mammalian or bacterial cells. This is because the molecular target of the toxic protein may not be present in plants, and even if it is present, the toxic protein can be sequestered in subcellular compartments such as the vacuole, which separates the product from its target.

Adenovirus Vectors Are A Powerful Tool for Vaccine Development And Gene Therapy

Adenoviruses have long been a popular viral vector for gene therapy because they are able to affect both replicating and non-replicating cells, accommodate large transgenes, and encode proteins without integrating into the host cell genome. More specifically, they are used as vectors to load recombinant DNA or protein therapeutics for targeted therapy by infecting targeted cells.

Lipid Nanoparticles (LNPs) in RNA Therapeutics: Transforming mRNA Vaccines, Cancer Immunotherapy, and CRISPR Delivery

In recent years, a once-obscure drug delivery technology has risen to prominence—lipid nanoparticles (LNPs). From mRNA vaccines and cancer immunotherapy to cutting-edge gene editing, LNPs are redefining the landscape of modern medicine.

ENVLPE: A Revolutionary Breakthrough in Gene Editing Delivery Technology

On April 9, 2025, a groundbreaking study published in Cell introduced a novel delivery technology called ENVLPE (Engineered Nucleocytosolic Vehicles for Loading of Programmable Editors), developed by a team of scientists from the Helmholtz Munich Center and the Technical University of Munich.

Merus' Bispecific Antibody Zenocutuzumab Rewrites Treatment History for NRG1 Fusion Tumors

Zenocutuzumab's FDA approval for NRG1 fusion-driven cancers ends a 30-year gap in HER3-targeted therapies, demonstrating strong efficacy in advanced pancreatic and lung cancers. Discover Creative Biogene's bispecific antibody development services today.

Unraveling Ubiquitination: Top Five Research Directions Transforming Cellular Regulation and Therapeutic Approaches

Merus’ Zenocutuzumab, a HER2/HER3 bispecific antibody, has received FDA accelerated approval for treating advanced pancreatic and lung cancers with NRG1 fusions, marking a breakthrough in cancer treatment. This innovative therapy offers new insights into dynamic signaling regulation and bispecific antibody development.

The Tumor Microenvironment: A New Frontier in Cancer Research

Cancer remains one of the most significant health challenges humanity faces, and its complexity and persistence compel researchers to explore new perspectives to understand and combat this disease.

The Breakthrough Potential of Oligonucleotide Drugs

Oligonucleotide drugs are short sequences of nucleotides designed to interact with specific target molecules within cellular pathways. These drugs include antisense oligonucleotides, small interfering RNAs, microRNA, and aptamers.

Recent Advances in Optogenetics and Six Major Research Directions

Optogenetics represents a cutting-edge technology that integrates optical methods with genetic engineering to enable precise control over neuronal activity in living animals. This technology allows researchers to manipulate the activity of specific types of neurons within the brain, spinal cord, and peripheral nerves, including those in freely moving animals.

* For research use only. Not intended for any clinical use.

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