Research Resource

Creative Biogene is committed to providing high quality products and services to help scientists around the world find solutions in biological research and drug discovery.

Research Areas

Adeno-Associated Viral Vectors in Neuroscience Research

Adeno-associated viral vectors (AAVs) are increasingly useful preclinical tools in neuroscience research studies for interrogating cellular and neurocircuit functions and mapping brain connectivity. Clinically, AAVs have for transformative research and therapeutics in the neurosciences.

Recombinase AAV Particles in Animal Experiments and Neurological Applications

The successful execution of neurobiology studies requires methods that are highly targetable, efficient, and precise. The arsenal of new sensors, actuators, recombinases, genes, RNA and base editing enzymes, and other genetically encoded tools for studying the nervous system is rapidly growing.

Application Prospects of Reporter Cell Lines

The reporter cell lines have shown great potential for cell tracing, drug development and gene function studies, etc. Creative Biogene offers reporter cell lines with high sensitivity and accurate localization, which have become a powerful tool of choice for researchers.

Application of Kinase Stable Cell Lines Detection of Secondary EGFR Mutations in Afatinib-Resistant BaF3 Cells

Kinases serve as key regulatory molecules for most cellular pathways, which are often associated with diseases: as causative agents for diseases, especially many cancers, or as targets for drug development.

AAV-HBV Transfection Mouse Model Efficient for Animal Experiments and HBV-Related Studies

Despite the availability of effective vaccination, hepatitis B virus (HBV) infection continues to be a major challenge worldwide. The exceptionally limited host spectrum of HBV has limited the research progress.

Viral Vector-Based Gene Therapy in Clinical Applications

Gene therapies are currently one of the most investigated therapeutic modalities in both the preclinical and clinical settings and have shown promise in treating a diverse spectrum of diseases.

TMEFF2: A New Target for Multiple Cancers

Transmembrane protein with an EGF-like and two Follistatin-like domains 2 (TMEFF2) is a 374-residue long type-I transmembrane proteoglycan which is proteolytically shed from the cell surface.

HER2 As an Ideal Target for Antibody Drugs

The long-sought discovery of HER2 as an actionable and highly sensitive therapeutic target was a major breakthrough for the treatment of highly aggressive HER2-positive breast cancer, leading to approval of the first HER2-targeted drug-the monoclonal antibody trastuzumab-almost 25 years ago.

Prospects of RNAi in Cancer Therapy

RNA interference (RNAi), a process that involves sequence-specific gene silencing, is an endogenous post-transcriptional regulation process that consists of non-coding RNAs like microRNAs (miRNAs), small interfering RNAs (siRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs)...

Application of RNA-Seq Technology in Cancer Research

Over the past few decades, RNA sequencing has significantly progressed, becoming a paramount approach for transcriptome profiling.

* For research use only. Not intended for any clinical use.

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