Research Resource

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Research Areas

Application of HEK293 Cell Line in the Production of Recombinant Proteins and Viral Vectors

The HEK293 cell line was established by transforming human embryonic kidney cells with sheared adenovirus type 5 DNA. Since then, many subtypes and derivatives have been established, with HEK293, HEK293-T, and HEK293-F frequently used in the production of biopharmaceuticals.

The Role of CAR-NK Cells in Cancer Cellular Immunotherapy

This article describes the unique advantages of CAR-NK cells, their production and application in cancer cell immunotherapy.

Role of Virus-like Particles in Nanovaccines and Drug Nanocarriers

This review discusses the process of production and manufacture of VLPs and their application as vaccines in the prevention of infectious diseases and cancers caused by the interaction of humoral and cellular immune systems.

Oncolytic Virus in Cancer Immunotherapy

This review summarizes the recent advances in the use of oncolytic viruses in biological therapy for cancer and sheds light on the future prospects.

Research of The Molecular Mechanism of NARF in Promoting Breast Cancer Metastasis

Breast cancer is the leading cause of cancer death for women globally, and the vast majority of breast cancer–related deaths are due to metastasis. Advanced breast cancers are characterized by intratumoral hypoxia, which is associated with metastasis, treatment failure, and patient mortality.

Research of Biological Functions and Potential Molecular Mechanisms of TTC9 Gene in Lung Adenocarcinoma

Lung adenocarcinoma (LUAD) is one of the most commonly diagnosed subtypes of lung cancer, and one of the deadliest cancers. Tetratricopeptide repeat domain 9A (TTC9) is upregulated and has played an oncogenic role in some malignant tumors. However, the expression and role of TTC9 has not yet been elucidated in LUAD.

Research of RECS1 Controlled Lysosome-mediated Cell Death

Programmed cell death is regulated by the balance between activating and inhibitory signals. RECS1 is a member of the evolutionarily conserved TMBIM superfamily and, more specifically, the LFG family of cell death regulators. Although the role of these proteins as inhibitors of cell death is well documented, the possible existence of proapoptotic members remained elusive.

Research of The Role of CLN7 in The Regulation of Lysosomal Function

Lysosomes play a vital role in eliminating worn-out proteins, damaged organelles, and other unnecessary materials in eukaryotic cells. Dysfunction of lysosomes often leads to lysosomal storage diseases (LSDs), which are characterized by abnormal accumulation of unmetabolized substrates within lysosomes.

Adaptor Protein Complex Interaction Map in Arabidopsis Identifies P34 as A Common Stability Regulator

Transport and distribution of biomolecules between plant cell endomembrane systems are essential for plant growth and development. Adaptor Protein (AP) is an evolutionarily very conserved class of complexes that are involved in the fine regulation of endosomal transport in plants.

Research on The Regulatory Mechanism of Manganate Pathway to Enhance Plant Carbon Dioxide Conversion

Terrestrial plants can convert atmospheric CO₂ into diverse and abundant aromatic compounds, thus providing high-value chemicals and considerable promise for carbon storage.

* For research use only. Not intended for any clinical use.

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