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- Transfected Stable Cell Lines
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  Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
  Transfected Stable Cell Lines
- Premade Virus Particles
  Ready-to-Use | High Titer | Versatile Applications
  Premade AAV, adenovirus, lentivirus particles, safe, stable, in stock.
  Premade Virus Particles
- Virus-Like Particles (VLPs)
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  Advanced VLPs for vaccine development (Chikungunya, Dengue, SARS-CoV-2), gene therapy (AAV1 & AAV9), and drug screening (SSTR2, CCR5).
  Virus-Like Particles (VLPs)
- Oligonucleotide Products
  Precise | High Yield | Tailored Solutions
  Accelerate your research with cost-effective LncRNA qPCR Array Technology.
  Oligonucleotide Products
- RNA Interference Products
  Targeted | Potent | High Specificity
  Human Druggable Genome siRNA Library enables efficient drug target screening.
  RNA Interference Products
  - shRNA Clones
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- Recombinant Drug Target Proteins
  Authentic | Versatile | Accelerated
  Providing functional, high-purity recombinant proteins—including membrane proteins and nanodiscs—to overcome bottlenecks in drug screening and target validation.
  Recombinant Drug Target Proteins
- Clones
  Validated | Reliable | Comprehensive Collection
  Ready-to-use clones for streamlined research and development.
  Clones
- Kits
  Complete | Convenient | High Sensitivity
  Chromogenic LAL Endotoxin Assay Kit ensures precise, FDA-compliant endotoxin quantification for biosafety testing.
  Kits
- Enzymes
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  Powerful Tn5 Transposase for DNA insertion and random library construction.
  Enzymes
  - Modified Enzyme
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- Aptamers
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  Aptamers for key proteins like ACVR1A, Akt, EGFR, and VEGFR.
  Aptamers
- Adjuvants
  Enhancing | Synergistic | Effective
  Enhance immune responses with high-purity, potent CpG ODNs.
  Adjuvants
- Laboratory Equipment
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  Effortlessly streamline DNA extraction with CB™ Magnetic-Nanoparticle Systems.
  Laboratory Equipment
Services
- Stable Cell Line Generation
  Reliable | Scalable | Customizable
  Fast proposals, regular updates, and detailed reports; strict quality control, and contamination-free cells; knockout results in 4-6 weeks.
  Stable Cell Line Generation
- Target-based Drug Discovery Service
  Innovative | Comprehensive | Efficient
  Target identification, validation, and screening for drug discovery and therapeutic development.
  Target-based Drug Discovery Service
- Custom Viral Service
  Versatile | High-Yield | Safe
  Unbeatable pricing, fully customizable viral packaging services (covering 30,000+ human genes, 200+ mammals, 50+ protein tags).
  Custom Viral Service
- Custom Antibody Service
  Precise | Flexible | Efficient
  End-to-end antibody development support, from target to validation, enabling clients to rapidly obtain application-ready antibodies.
  Custom Antibody Service
- Antibody-Drug Conjugation Service
  Integrated | Controlled | Translational
  Comprehensive solutions covering design, development, and validation to ensure conjugated drugs with consistent quality and clinical potential.
  Antibody-Drug Conjugation Service
- Protein Degrader Service
  Efficient | High-Precision | Advanced Therapeutics
  Harness the power of protein degraders for precise protein degradation, expanding druggable targets and enhancing therapeutic effectiveness for cutting-edge drug discovery.
  Protein Degrader Service
- Nucleotides Service
  Accurate | Flexible | High-Quality
  Custom synthesis of oligonucleotides, primers, and probes for gene editing, PCR, and RNA studies.
  Nucleotides Service
- Custom RNA Service
  Custom RNA ServicePrecise | Flexible | GMP-ReadyCustom
  RNA design, synthesis, and manufacturing—covering mRNA, saRNA, circRNA, and RNAi. Fast turnaround, rigorous QC, and seamless transition from research to GMP production.
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- Custom Libraries Construction Service
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  Custom cDNA, genomic, and mutagenesis libraries for drug discovery, screening, and functional genomics.
  Custom Libraries Construction Service
- Gene Editing Services
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  Gene editing solutions for gene editing, knockouts, knock-ins, and customized genetic modifications. Integrated multi-platform solutions for one-stop CRISPR sgRNA library synthesis and gene screening services
  Gene Editing Services
- Microbe Genome Editing Service
  Precise | Scalable | Customizable
  Enhance microbial productivity with advanced genome editing using Rec-mediated recombination and CRISPR/Cas9 technologies.
  Microbe Genome Editing Service
  - CRISPR Based Microbe Genome Editing Service
  - Recombineering Based Microbe Genome Editing Service
- Biosafety Testing Service
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  Complete biosafety testing solutions for gene therapy, viral vectors, and biologics development.
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- Plant Genetic Modification Service
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  Genetic modification for crop improvement, biotechnology, and plant-based research solutions.
  Plant Genetic Modification Service
- Plant-based Protein Production Service
  Efficient | Scalable | Customizable
  Plant-based protein expression systems for biopharmaceuticals, enzyme production, and research.
  Plant-based Protein Production Service
  - Plant Cell Suspension-based Protein Production
  - Rice Endosperm-Specific Expression System
- Aptamer Discovery & SELEX Solutions
  Innovative | Fast | Cost-Effective
  Revolutionizing drug delivery and diagnostic development with next-generation high-throughput aptamer selection and synthesis technologies.
  Aptamer Discovery & SELEX Solutions
  - Aptamers Services
  - Technology Platforms
Applications
- Membrane Proteome Chip Antibody Off-Target Screening Service
  Membrane Proteome Chip Antibody Off‑Target Screening
  Native‑conformation | Quantitative | Cross‑reactivity free
  Membrane Proteome Chip Antibody Off-Target Screening Service
- CGT Biosafety Testing
  Comprehensive | Accurate | Regulatory-compliant
  Internationally certified evaluation system for biologics, gene therapies, nucleic acid drugs, and vaccines.
  CGT Biosafety Testing
- Pandemic Detection Solutions
  Rapid | Precise | Scalable
  Balancing accuracy, accessibility, affordability, and rapid detection to safeguard public health and strengthen global response to infectious diseases.
  Pandemic Detection Solutions
CDMO
- HEK293 Cell-Based Production Platform
- cGMP Cell Line Development
  Reliable | Scalable | Industry-leading
  Stable expression over 15 generations with rapid cell line development in just 3 months.
  Supports adherent and suspension cell lines, offering MCB, WCB, and PCB establishment.
  cGMP Cell Line Development
- GMP mRNA Production
  Efficient | Scalable | Precise
  Scalable mRNA production from milligrams to grams, with personalized process design for sequence optimization, cap selection, and nucleotide modifications, all in one service.
  GMP mRNA Production
- GMP Plasmid Production
  High Quality | Scalable | Regulatory-compliant
  Our plasmid production services span Non-GMP, GMP-Like, and GMP-Grade levels, with specialized options for linearized plasmids.
  GMP Plasmid Production
- GMP Viral Vector Manufacturing
  Scalable | High Yield | Quality-driven
  Advanced platforms for AAV, adenovirus, lentivirus, and retrovirus production, with strict adherence to GMP guidelines and robust quality control.
  GMP Viral Vector Manufacturing
AI
- AI-Driven Gene Editing and Therapy
  Innovative | Precision | Transformative
  AI-powered one-click design for customized CRISPR gene editing strategy development.
  AI-Driven Gene Editing and Therapy
- AI-Antibody Engineering Fusion
  Next-Generation | Targeted | Efficient
  AI and ML algorithms accelerate antibody screening and predict new structures, unlocking unprecedented possibilities in antibody engineering.
  AI-Antibody Engineering Fusion
- AI-Driven Enzyme Engineering
  Smart | Efficient | Tailored
  High-throughput enzyme activity testing with proprietary datasets and deep learning models for standardized and precise enzyme engineering design.
  AI-Driven Enzyme Engineering
- AI-Enhanced Small Molecule Screening
  Predictive | Efficient | Insightful
  Leverage AI to uncover hidden high-potential small molecules, prioritize leads intelligently, and reduce costly trial-and-error in early drug discovery.
  AI-Enhanced Small Molecule Screening
- AI-Driven Protein Degrader Drug Development
  Innovative | Targeted | Accelerated
  Use AI-guided design to optimize protein degraders, addressing design complexity and enhancing efficacy while shortening development timelines.
  AI-Driven Protein Degrader Drug Development
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Protein Biology

Development, Principles, and Methodological Advances of Yeast Two-Hybrid Technology

Development, Principles, and Methodological Advances of Yeast Two-Hybrid Technology

Yeast two-hybrid (Y2H) technology is a cornerstone method for probing protein–protein interactions directly within living cells. From its classical nuclear format to membrane-based, cytosolic, split-protein, and sequencing-enabled variants, Y2H has continuously evolved to address increasingly complex biological questions. These methodological advances enable the analysis of diverse protein classes and support scalable interaction discovery, from focused validation to systems-level interactome mapping. Today, Y2H remains a versatile and powerful platform for elucidating cellular mechanisms, signaling networks, and disease-associated protein interactions.