GFP Reporter Cell Line - REH

The REH cell line, originating from a patient with acute lymphoblastic leukemia, has been extensively utilized in biomedical research due to its relevance in the study of hematopoietic malignancies. Established in the early 1970s, REH cells have served as a fundamental tool in elucidating various aspects of leukemia biology, including molecular mechanisms underlying disease progression and therapeutic responses. Over the years, researchers have harnessed the potential of REH cells to investigate genetic alterations, signaling pathways, and drug sensitivities pertinent to leukemia pathogenesis. The development of REH cells stably expressing Green Fluorescent Protein (GFP) reporter has significantly enhanced their utility in cellular imaging studies and high-throughput screening assays. The GFP reporter system enables real-time visualization and quantification of cellular processes, facilitating the assessment of dynamic cellular behaviors, such as proliferation, migration, and differentiation. This innovative approach has greatly expedited the identification of novel therapeutic targets and evaluation of drug efficacy in leukemia research. The REH cell line, established decades ago, continues to be a cornerstone in leukemia research, providing valuable insights into disease mechanisms and serving as a platform for drug discovery endeavors. The integration of GFP reporter technology further augments the versatility of REH cells, enabling precise and comprehensive investigations into leukemia biology.