Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CSC-RR0248
Host Cell : A375 Size : >1x106 frozen cells/vial
| Cat. No. | CSC-RR0248 |
| Description | GFP Reporter Cell Line-A375 is engineered to stably overexpress GFP reporter gene. It is an ideal positive control for use in fluorescence assays. In vivo fluorescent imaging is not recommended due to high background autofluorescence. |
| Target Gene | GFP |
| Host Cell | A375 |
| Host Cell Species | Homo sapiens (Human) |
| Reporter Type | Fluorescent protein |
| Applications |
1. Gene expression studies 2. Protein localization 3. Drug screening and toxicology 4. Live cell imaging |
| Size | >1x106 frozen cells/vial |
| Stability | Validated for at least 10 passages |
| Quality Control | Negative for bacteria, yeast, fungi and mycoplasma. |
| Storage | Liquid nitrogen |
| Shipping | Dry ice |
| Revival | Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media. |
| Mycoplasma | Negative |
| Format | One frozen vial containing millions of cells |
| Storage | Liquid nitrogen |
| Safety Considerations |
The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach. |
| Ship | Dry ice |
A237 Cell Line is a human melanoma cell line that has been widely used in skin cancer research. Derived from a primary melanoma tumor, this cell line retains many of the characteristics of the original tumor, making it a valuable tool for studying the development and progression of melanoma.
One of the key features of A237 Cell Line is its high level of invasive potential, which allows researchers to study the invasive behavior of melanoma cells and understand the mechanisms underlying tumor metastasis. This information is crucial for developing new strategies to prevent and treat melanoma metastasis.
Additionally, A237 Cell Line has been found to have high expression levels of various oncogenes and tumor suppressor genes, making it an ideal model for studying the genetic and molecular events involved in melanoma formation. By studying these genes and their interactions, researchers can gain a better understanding of the pathogenesis of melanoma and develop new diagnostic and therapeutic methods.
Furthermore, A237 Cell Line has been used in drug screening and toxicity tests. Its high invasive potential and genetic instability make it a useful model for evaluating the efficacy and safety of new anticancer drugs.
A237 Cell Line is an important tool for studying melanoma, providing researchers with a model that closely resembles the characteristics of the disease in humans. Its high invasive potential and genetic instability make it a valuable resource for investigating the pathogenesis of melanoma and developing new treatments.
A: A375 Cell Line is significant for drug testing as it can be used to screen the effectiveness of potential anti-melanoma drugs and to study the mechanisms of action of known therapies, aiding in the development of new treatments for melanoma.
A: A375 Cell Line is valuable for melanoma research due to its ability to grow rapidly in culture and its retention of characteristics similar to those of primary melanoma tumors.
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The GFP reporter cell line - A375 produces a strong and stable fluorescent signal, which is perfect for my research purposes.
This cell line proved to be safe and efficient in my experiments, providing reliable and accurate data.
The GFP Reporter Cell Line-A375 is easy to culture and handle, saving time and effort in my research activities.
The product performs well and is reasonably priced, making it a cost-effective solution for my research needs.
The GFP Reporter Cell Line-A375 consistently provides reliable and reproducible results, which is essential for my research.
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