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Cytokines & Growth Factors

Cytokines and growth factors are central mediators of cell–cell communication, regulating immune responses, tissue homeostasis, development, and regeneration. Recombinant cytokine and growth factor proteins provide essential tools for studying signaling pathways, cellular responses, and disease-associated biological processes.

Our Cytokine and Growth Factor recombinant protein portfolio is designed to support biologically relevant and experimentally reliable research, with careful attention to protein conformation, expression systems, and application-oriented quality control.

Built for Signaling and Cell-Based Research

Cytokines and growth factors are highly context-dependent molecules whose biological effects rely on correct folding, receptor engagement, and concentration-dependent signaling. This portfolio is developed to support a broad range of signaling- and response-driven research workflows.

Cell Signaling and Pathway Activation Studies

Recombinant cytokines and growth factors are widely used to activate defined signaling pathways, supporting studies of downstream transcriptional, metabolic, and functional responses in immune and non-immune cell systems.

Cell Proliferation, Differentiation, and Survival Assays

Growth factors and cytokines play critical roles in regulating cell fate decisions. These proteins are suitable for use in cell proliferation, differentiation, survival, and maintenance assays across diverse cell types.

Immune Modulation and Inflammatory Research

Cytokines involved in immune activation, inflammation, and immune regulation support mechanistic studies of immune responses, cytokine networks, and disease-associated immune dysregulation.

Receptor Engagement and Functional Validation

Recombinant cytokines and growth factors serve as functional ligands for validating receptor expression, receptor–ligand interactions, and signaling competence in biochemical and cell-based systems.

Broad and Flexible Portfolio Coverage

The portfolio includes a wide range of cytokines, chemokines, and growth factors involved in immune regulation, inflammation, angiogenesis, tissue repair, and development.

Coverage includes:

  • Interleukins and cytokines involved in immune activation and regulation
  • Chemokines supporting cell migration and inflammatory signaling
  • Growth factors associated with angiogenesis, tissue remodeling, and regeneration
  • Members of the TNF superfamily and related signaling ligands

Multiple species options are available, including human, mouse, cynomolgus, rhesus macaque, rat, and bovine proteins, supporting translational and comparative research.

Protein Design Optimized for Biological Activity

Cytokine and growth factor functionality depends strongly on correct tertiary structure and receptor-binding interfaces. Protein constructs are designed to preserve biologically active regions while supporting experimental flexibility.

Multiple formats are available, including:

  • Tag-free proteins for native signaling studies
  • His-tagged constructs for biochemical assays and purification compatibility
  • Fc-fusion formats to enhance stability, avidity, or assay performance
  • Biotinylated proteins for receptor binding and interaction studies

Expression systems are selected based on the structural and functional requirements of each protein, including mammalian and bacterial platforms.

Quality Attributes Supporting Sensitive Assay Systems

Due to the potency of cytokines and growth factors, consistent quality and controlled impurity profiles are essential. Each recombinant protein is produced under standardized quality control processes aligned with sensitive cell-based and signaling assays.

Key quality attributes include:

  • High purity and defined molecular profiles
  • Low endotoxin levels suitable for cytokine-responsive systems
  • Batch-to-batch consistency
  • Quality evaluation strategies aligned with biological activity and assay performance

Available Recombinant Proteins

Supporting Discovery and Translational Research

This Cytokine and Growth Factor recombinant protein portfolio is supplied for research use only and is designed to support both fundamental biological studies and translational research programs. Broad target coverage, multiple construct formats, and application-oriented design enable flexible integration into diverse experimental workflows.

For detailed product specifications, available formats, or technical support, please explore individual product pages or contact our technical support team.

* For research use only. Not intended for any clinical use.
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