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Cell line development is one of the most important steps in establishing a biopharmaceutical production process. The process of developing stable cell lines starts with the transfection of host cells (CHO or HEK 293) with recombinant plasmids or cell fusion of hybridomas. From DNA vector design and constructs to the selection of top production clones, a well-designed cell line development strategy is required to obtain the best solution for GMP production. At Creative Biogene, we combine high-producing cell lines with custom expression vectors that are integrated into pool and minipool selection programs, thereby increasing the likelihood of identifying high producer clones.
Expression vectors are an important tool for protein production. Carefully designed expression vectors enhance, stabilize expression and increase secretion. Creative Biogene is committed to using our expertise to provide genetic elements that have been carefully selected for expression cassettes and to provide codon optimization services for stable expression and production.
Creative Biogene provides the most suitable cell expression vectors carefully selected according to the customer's production demands.
To ensure that your cell line is highly productive from the start, we support the design of your target gene with codon optimization and our in-house library of signaling peptides.
Craetive Biogene has extensive experience in gene synthesis and we are committed to applying our expertise in synthesizing high quality DNA.
Creative Biogene scientists construct the most appropriate expression vectors for our clients based on the characteristics of the gene sequence. We carefully design expression vectors to enhance, and stabilize, the expression of target molecules.
Creative Biogene sequences target sequences and analyzes them for validation using our advanced sequencing technology to ensure the quality and correctness of the DNA used for stable cell line construction.
As a leading provider of GMP cell line development services, Creative Biogene is committed to applying our expertise to provide our customers with well-designed cell line expression vectors from the source, enabling robust and efficient cell line development. Please feel free to contact us if you have a need, and our experienced specialists will be happy to assist you.
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