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Immune & Cell Surface Receptors

Cell surface receptors define how immune cells sense, interpret, and respond to their microenvironment. From immune activation and inhibition to cytokine signaling and cell–cell recognition, these receptors act as the primary interface between extracellular cues and intracellular decision-making.

Creative Biogene's recombinant immune and cell surface receptor proteins are developed as reliable research tools to support mechanistic immunology, translational studies, and early-stage drug discovery.

Cell Surface Receptors in Immune Regulation

Immune cell behavior is orchestrated through a complex network of surface-expressed receptors that regulate:

  • Immune activation and inhibitory signaling
  • Cytokine and growth factor responsiveness
  • Cell–cell interaction and immune synapse formation
  • Immune tolerance, exhaustion, and checkpoint control

Recombinant receptor proteins offer defined extracellular domains for the controlled in vitro interrogation of these pathways.

Application-Oriented Research Scenarios

This product portfolio supports a broad range of immunology and cell signaling applications, including:

Immune Checkpoint and Myeloid Regulation Studies

Supporting investigation of receptor–ligand interactions involved in immune suppression, tolerance, and myeloid cell function.

Cytokine and Costimulatory Signaling

Enabling functional studies of cytokine receptor engagement and costimulatory pathways relevant to immune activation and differentiation.

Cell–Cell Interaction and Adhesion Research

Facilitating analysis of receptor-mediated immune cell communication, trafficking, and tissue-specific immune responses.

Translational and Preclinical Model Development

Providing cross-species receptor tools to support comparative studies and translational validation.

Broad Coverage Across Immune Receptor Families

Our immune and cell surface receptor portfolio includes recombinant proteins representing diverse functional classes, such as:

  • Immunoglobulin superfamily receptors
  • TNF receptor and ligand family members
  • C-type lectins and pattern recognition receptors
  • Cytokine receptor subunits
  • Adhesion and guidance receptors

Multiple formats are available, including Fc fusion, His-tagged, and biotinylated proteins, enabling flexible experimental design.

Designed for Functional and Binding Studies

These recombinant receptors are commonly applied in:

  • Ligand–receptor binding and competition assays
  • Cell-based functional assays
  • Immune signaling pathway reconstruction
  • Antibody and biologic screening workflows

By focusing on extracellular domain integrity and molecular consistency, the proteins integrate seamlessly into immunological assay systems.

Protein Quality and Production Standards

All immune and cell surface receptor proteins are produced using mammalian expression systems to ensure proper folding and post-translational processing. Each product is manufactured under standardized workflows featuring:

  • High purity validated by orthogonal analytical methods
  • Low endotoxin levels suitable for immune-related studies
  • Lot-to-lot consistency supporting reproducibility
  • Research-ready formats compatible with diverse assay platforms

Available Recombinant Proteins

Explore Immune & Cell Surface Receptor Proteins

Browse our comprehensive selection of recombinant immune and cell surface receptor proteins to identify tools that align with your research objectives. Custom formats, species variants, and related ligands are available upon request.

* For research use only. Not intended for any clinical use.
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