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- Transfected Stable Cell Lines
  
  Reliable | High-Performance | Wide Rage
  
  Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
  
  Transfected Stable Cell Lines
- Premade Virus Particles
  
  Ready-to-Use | High Titer | Versatile Applications
  
  Premade AAV, adenovirus, lentivirus particles, safe, stable, in stock.
  
  Premade Virus Particles
- Virus-Like Particles (VLPs)
  
  Stable | Scalable | Customizable
  
  Advanced VLPs for vaccine development (Chikungunya, Dengue, SARS-CoV-2), gene therapy (AAV1 & AAV9), and drug screening (SSTR2, CCR5).
  
  Virus-Like Particles (VLPs)
- Oligonucleotide Products
  
  Precise | High Yield | Tailored Solutions
  
  Accelerate your research with cost-effective LncRNA qPCR Array Technology.
  
  Oligonucleotide Products
- RNA Interference Products
  
  Targeted | Potent | High Specificity
  
  Human Druggable Genome siRNA Library enables efficient drug target screening.
  
  RNA Interference Products
  - shRNA Clones
  - siRNA Libraries
- Recombinant Drug Target Proteins
  
  Authentic | Versatile | Accelerated
  
  Providing functional, high-purity recombinant proteins—including membrane proteins and nanodiscs—to overcome bottlenecks in drug screening and target validation.
  
  Recombinant Drug Target Proteins
  - Nanodiscs
- Clones
  
  Validated | Reliable | Comprehensive Collection
  
  Ready-to-use clones for streamlined research and development.
  
  Clones
- Kits
  
  Complete | Convenient | High Sensitivity
  
  Chromogenic LAL Endotoxin Assay Kit ensures precise, FDA-compliant endotoxin quantification for biosafety testing.
  
  Kits
- Enzymes
  
  Purified | Stable | Efficient
  
  Powerful Tn5 Transposase for DNA insertion and random library construction.
  
  Enzymes
  - Modified Enzyme
  - Restriction Enzyme
- Aptamers
  
  Highly Specific | Robust | Versatile
  
  Aptamers for key proteins like ACVR1A, Akt, EGFR, and VEGFR.
  
  Aptamers
- Adjuvants
  
  Enhancing | Synergistic | Effective
  
  Enhance immune responses with high-purity, potent CpG ODNs.
  
  Adjuvants
- Laboratory Equipment
  
  Innovative | Reliable | High-Precision
  
  Effortlessly streamline DNA extraction with CB™ Magnetic-Nanoparticle Systems.
  
  Laboratory Equipment
Services
- Stable Cell Line Generation
  
  Reliable | Scalable | Customizable
  
  Fast proposals, regular updates, and detailed reports; strict quality control, and contamination-free cells; knockout results in 4-6 weeks.
  
  Stable Cell Line Generation
- Target-based Drug Discovery Service
  
  Innovative | Comprehensive | Efficient
  
  Target identification, validation, and screening for drug discovery and therapeutic development.
  
  Target-based Drug Discovery Service
- Custom Viral Service
  
  Versatile | High-Yield | Safe
  
  Unbeatable pricing, fully customizable viral packaging services (covering 30,000+ human genes, 200+ mammals, 50+ protein tags).
  
  Custom Viral Service
- Custom Antibody Service
  
  Precise | Flexible | Efficient
  
  End-to-end antibody development support, from target to validation, enabling clients to rapidly obtain application-ready antibodies.
  
  Custom Antibody Service
- Antibody-Drug Conjugation Service
  
  Integrated | Controlled | Translational
  
  Comprehensive solutions covering design, development, and validation to ensure conjugated drugs with consistent quality and clinical potential.
  
  Antilbody-drug Conjugation Service
- Protein Degrader Service
  
  Efficient | High-Precision | Advanced Therapeutics
  
  Harness the power of protein degraders for precise protein degradation, expanding druggable targets and enhancing therapeutic effectiveness for cutting-edge drug discovery.
  
  Protein Degrader Service
- Nucleotides Service
  
  Accurate | Flexible | High-Quality
  
  Custom synthesis of oligonucleotides, primers, and probes for gene editing, PCR, and RNA studies.
  
  Nucleotides Service
- Custom RNA Service
  
  Custom RNA ServicePrecise | Flexible | GMP-ReadyCustom
  
  RNA design, synthesis, and manufacturing—covering mRNA, saRNA, circRNA, and RNAi. Fast turnaround, rigorous QC, and seamless transition from research to GMP production.
  
  Custom RNA Service
- Custom Libraries Construction Service
  
  Comprehensive | High-throughput | Accurate
  
  Custom cDNA, genomic, and mutagenesis libraries for drug discovery, screening, and functional genomics.
  
  Custom Libraries Construction Service
- Gene Editing Services
  
  Precise | Efficient | Targeted
  
  Gene editing solutions for gene editing, knockouts, knock-ins, and customized genetic modifications. Integrated multi-platform solutions for one-stop CRISPR sgRNA library synthesis and gene screening services
  
  Gene Editing Services
- Microbe Genome Editing Service
  
  Precise | Scalable | Customizable
  
  Enhance microbial productivity with advanced genome editing using Rec-mediated recombination and CRISPR/Cas9 technologies.
  
  Microbe Genome Editing Service
  - CRISPR Based Microbe Genome Editing Service
  - Recombineering Based Microbe Genome Editing Service
- Biosafety Testing Service
  
  Reliable | Comprehensive | Regulated
  
  Complete biosafety testing solutions for gene therapy, viral vectors, and biologics development.
  
  Biosafety Testing Service
- Plant Genetic Modification Service
  
  Advanced | Sustainable | Tailored
  
  Genetic modification for crop improvement, biotechnology, and plant-based research solutions.
  
  Plant Genetic Modification Service
- Plant-based Protein Production Service
  
  Efficient | Scalable | Customizable
  
  Plant-based protein expression systems for biopharmaceuticals, enzyme production, and research.
  
  Plant-based Protein Production Service
  - Plant Cell Suspension-based Protein Production
  - Rice Endosperm-Specific Expression System
- Aptamers Service
  
  Innovative | Fast | Cost-Effective
  
  Revolutionizing drug delivery and diagnostic development with next-generation high-throughput aptamer selection and synthesis technologies.
  
  Aptamers Service
  - Aptamers Services
  - Technology Platforms
Applications
- CGT Biosafety Testing
  
  Comprehensive | Accurate | Regulatory-compliant
  
  Internationally certified evaluation system for biologics, gene therapies, nucleic acid drugs, and vaccines.
  
  CGT Biosafety Testing
- Pandemic Detection Solutions
  
  Rapid | Precise | Scalable
  
  Balancing accuracy, accessibility, affordability, and rapid detection to safeguard public health and strengthen global response to infectious diseases.
  
  Pandemic Detection Solutions
CDMO
- cGMP Cell Line Development
  
  Reliable | Scalable | Industry-leading
  
  Stable expression over 15 generations with rapid cell line development in just 3 months.
  Supports adherent and suspension cell lines, offering MCB, WCB, and PCB establishment.
  
  cGMP Cell Line Development
- GMP mRNA Production
  
  Efficient | Scalable | Precise
  
  Scalable mRNA production from milligrams to grams, with personalized process design for sequence optimization, cap selection, and nucleotide modifications, all in one service.
  
  GMP mRNA Production
- GMP Plasmid Production
  
  High Quality | Scalable | Regulatory-compliant
  
  Our plasmid production services span Non-GMP, GMP-Like, and GMP-Grade levels, with specialized options for linearized plasmids.
  
  GMP Plasmid Production
- GMP Viral Vector Manufacturing
  
  Scalable | High Yield | Quality-driven
  
  Advanced platforms for AAV, adenovirus, lentivirus, and retrovirus production, with strict adherence to GMP guidelines and robust quality control.
  
  GMP Viral Vector Manufacturing
AI
- AI-Driven Gene Editing and Therapy
  
  Innovative | Precision | Transformative
  
  AI-powered one-click design for customized CRISPR gene editing strategy development.
  
  AI-Driven Gene Editing and Therapy
- AI-Antibody Engineering Fusion
  
  Next-Generation | Targeted | Efficient
  
  AI and ML algorithms accelerate antibody screening and predict new structures, unlocking unprecedented possibilities in antibody engineering.
  
  AI-Antibody Engineering Fusion
- AI-Driven Enzyme Engineering
  
  Smart | Efficient | Tailored
  
  High-throughput enzyme activity testing with proprietary datasets and deep learning models for standardized and precise enzyme engineering design.
  
  AI-Driven Enzyme Engineering
- AI-Enhanced Small Molecule Screening
  
  Predictive | Efficient | Insightful
  
  Leverage AI to uncover hidden high-potential small molecules, prioritize leads intelligently, and reduce costly trial-and-error in early drug discovery.
  
  AI-Enhanced Small Molecule Screening
- AI-Driven Protein Degrader Drug Development
  
  Innovative | Targeted | Accelerated
  
  Use AI-guided design to optimize protein degraders, addressing design complexity and enhancing efficacy while shortening development timelines.
  
  AI-Driven Protein Degrader Drug Development
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Modified Enzyme

Brief Introduction

Modified Enzyme

Creative Biogene’s modification enzymes, including DNA and RNA polymerases, phosphatases, kinases, ligases, nucleases, methyltransferases, DNA repair proteins, recombinases etc, are used for a variety of molecular biology applications such as PCR amplification, cDNA synthesis, ligation of blunt or cohesive-ended DNA fragments, phosphorylation & dephosphorylation, methylation & demethylation, nucleic acid manipulation, and DNA repair research and study of UV damaged DNA etc.

Creative Biogene has years of enzyme production experience, and all enzymes are tested in standard functional assays and certified free of nucleases and proteases.

* For research use only. Not intended for any clinical use.

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