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Pseudoviruses (PsV) are closely related to the structures and characteristics of its native viruses, but lack some characteristics of the native viruses such as capability for replication. The HPV PsV system has been widely used in the HPV research field because the property of HPV PsV is similar to that of native HPV virion. The capsid of HPV consists of 72 homo-pentameric capsomers of the major structural protein L1 and a variable number (12–72 copies) of the minor structural protein L2. L1 and L2 proteins can be assembled spontaneously into virus-like particles (VLPs) and package either HPV viral genome or non-viral DNA.
At Creative Biogene, our scientists have developed a panel of HPV Pseudoviruses (PsVs) that cover multiple HPV types such as HPV6, HPV11, HPV16, HPV18, HPV31, HPV33 etc. The viral genome of our PsVs was replaced with a pseudogenome which encodes a fluorescent and / or a bioluminescent reporter protein(s). Using the reporter signal as readout, these PsVs can be used for analyzing neutralization or infectious entry pathways.
Figure 1. Schematic diagram of HPV pseudovirus structure
| Cat.No. | Product Name | Price |
|---|---|---|
| HPVP-001 | HPV6-GFP Reporter Pseudovirus | Inquiry |
| HPVP-002 | HPV11-GFP Reporter Pseudovirus | Inquiry |
| HPVP-003 | HPV16-GFP Reporter Pseudovirus | Inquiry |
| HPVP-004 | HPV18-GFP Reporter Pseudovirus | Inquiry |
| HPVP-005 | HPV31-GFP Reporter Pseudovirus | Inquiry |
| HPVP-006 | HPV33-GFP Reporter Pseudovirus | Inquiry |
| HPVP-007 | HPV45-GFP Reporter Pseudovirus | Inquiry |
| HPVP-008 | HPV52-GFP Reporter Pseudovirus | Inquiry |
| HPVP-009 | HPV58-GFP Reporter Pseudovirus | Inquiry |
| HPVP-010 | HPV6-Luciferase Reporter Pseudovirus | Inquiry |
| HPVP-011 | HPV18-Luciferase Reporter Pseudovirus | Inquiry |
| HPVP-012 | HPV16-Luciferase Reporter Pseudovirus | Inquiry |
| HPVP-013 | HPV31-Luciferase Reporter Pseudovirus | Inquiry |
| HPVP-014 | HPV33-Luciferase Reporter Pseudovirus | Inquiry |
| HPVP-015 | HPV11-Luciferase Reporter Pseudovirus | Inquiry |
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