Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Premade Virus Particles
Ready-to-Use | High Titer | Versatile Applications
Premade AAV, adenovirus, lentivirus particles, safe, stable, in stock.
Virus-Like Particles (VLPs)
Stable | Scalable | Customizable
Advanced VLPs for vaccine development (Chikungunya, Dengue, SARS-CoV-2), gene therapy (AAV1 & AAV9), and drug screening (SSTR2, CCR5).
Oligonucleotide Products
Precise | High Yield | Tailored Solutions
Accelerate your research with cost-effective LncRNA qPCR Array Technology.
RNA Interference Products
Targeted | Potent | High Specificity
Human Druggable Genome siRNA Library enables efficient drug target screening.
Recombinant Drug Target Proteins
Authentic | Versatile | Accelerated
Providing functional, high-purity recombinant proteins—including membrane proteins and nanodiscs—to overcome bottlenecks in drug screening and target validation.
Clones
Validated | Reliable | Comprehensive Collection
Ready-to-use clones for streamlined research and development.
Kits
Complete | Convenient | High Sensitivity
Chromogenic LAL Endotoxin Assay Kit ensures precise, FDA-compliant endotoxin quantification for biosafety testing.
Enzymes
Purified | Stable | Efficient
Powerful Tn5 Transposase for DNA insertion and random library construction.
Aptamers
Highly Specific | Robust | Versatile
Aptamers for key proteins like ACVR1A, Akt, EGFR, and VEGFR.
Adjuvants
Enhancing | Synergistic | Effective
Enhance immune responses with high-purity, potent CpG ODNs.
Laboratory Equipment
Innovative | Reliable | High-Precision
Effortlessly streamline DNA extraction with CB™ Magnetic-Nanoparticle Systems.
Stable Cell Line Generation
Reliable | Scalable | Customizable
Fast proposals, regular updates, and detailed reports; strict quality control, and contamination-free cells; knockout results in 4-6 weeks.
Target-based Drug Discovery Service
Innovative | Comprehensive | Efficient
Target identification, validation, and screening for drug discovery and therapeutic development.
Custom Viral Service
Versatile | High-Yield | Safe
Unbeatable pricing, fully customizable viral packaging services (covering 30,000+ human genes, 200+ mammals, 50+ protein tags).
Custom Antibody Service
Precise | Flexible | Efficient
End-to-end antibody development support, from target to validation, enabling clients to rapidly obtain application-ready antibodies.
Antibody-Drug Conjugation Service
Integrated | Controlled | Translational
Comprehensive solutions covering design, development, and validation to ensure conjugated drugs with consistent quality and clinical potential.
Protein Degrader Service
Efficient | High-Precision | Advanced Therapeutics
Harness the power of protein degraders for precise protein degradation, expanding druggable targets and enhancing therapeutic effectiveness for cutting-edge drug discovery.
Nucleotides Service
Accurate | Flexible | High-Quality
Custom synthesis of oligonucleotides, primers, and probes for gene editing, PCR, and RNA studies.
Custom RNA Service
Custom RNA ServicePrecise | Flexible | GMP-ReadyCustom
RNA design, synthesis, and manufacturing—covering mRNA, saRNA, circRNA, and RNAi. Fast turnaround, rigorous QC, and seamless transition from research to GMP production.
Custom Libraries Construction Service
Comprehensive | High-throughput | Accurate
Custom cDNA, genomic, and mutagenesis libraries for drug discovery, screening, and functional genomics.
Gene Editing Services
Precise | Efficient | Targeted
Gene editing solutions for gene editing, knockouts, knock-ins, and customized genetic modifications. Integrated multi-platform solutions for one-stop CRISPR sgRNA library synthesis and gene screening services
Microbe Genome Editing Service
Precise | Scalable | Customizable
Enhance microbial productivity with advanced genome editing using Rec-mediated recombination and CRISPR/Cas9 technologies.
Biosafety Testing Service
Reliable | Comprehensive | Regulated
Complete biosafety testing solutions for gene therapy, viral vectors, and biologics development.
Plant Genetic Modification Service
Advanced | Sustainable | Tailored
Genetic modification for crop improvement, biotechnology, and plant-based research solutions.
Plant-based Protein Production Service
Efficient | Scalable | Customizable
Plant-based protein expression systems for biopharmaceuticals, enzyme production, and research.
Aptamers Service
Innovative | Fast | Cost-Effective
Revolutionizing drug delivery and diagnostic development with next-generation high-throughput aptamer selection and synthesis technologies.
CGT Biosafety Testing
Comprehensive | Accurate | Regulatory-compliant
Internationally certified evaluation system for biologics, gene therapies, nucleic acid drugs, and vaccines.
Pandemic Detection Solutions
Rapid | Precise | Scalable
Balancing accuracy, accessibility, affordability, and rapid detection to safeguard public health and strengthen global response to infectious diseases.
cGMP Cell Line Development
Reliable | Scalable | Industry-leading
Stable expression over 15 generations with rapid cell line development in just 3 months.
Supports adherent and suspension cell lines, offering MCB, WCB, and PCB establishment.
GMP mRNA Production
Efficient | Scalable | Precise
Scalable mRNA production from milligrams to grams, with personalized process design for sequence optimization, cap selection, and nucleotide modifications, all in one service.
GMP Plasmid Production
High Quality | Scalable | Regulatory-compliant
Our plasmid production services span Non-GMP, GMP-Like, and GMP-Grade levels, with specialized options for linearized plasmids.
GMP Viral Vector Manufacturing
Scalable | High Yield | Quality-driven
Advanced platforms for AAV, adenovirus, lentivirus, and retrovirus production, with strict adherence to GMP guidelines and robust quality control.
AI-Driven Gene Editing and Therapy
Innovative | Precision | Transformative
AI-powered one-click design for customized CRISPR gene editing strategy development.
AI-Antibody Engineering Fusion
Next-Generation | Targeted | Efficient
AI and ML algorithms accelerate antibody screening and predict new structures, unlocking unprecedented possibilities in antibody engineering.
AI-Driven Enzyme Engineering
Smart | Efficient | Tailored
High-throughput enzyme activity testing with proprietary datasets and deep learning models for standardized and precise enzyme engineering design.
AI-Enhanced Small Molecule Screening
Predictive | Efficient | Insightful
Leverage AI to uncover hidden high-potential small molecules, prioritize leads intelligently, and reduce costly trial-and-error in early drug discovery.
AI-Driven Protein Degrader Drug Development
Innovative | Targeted | Accelerated
Use AI-guided design to optimize protein degraders, addressing design complexity and enhancing efficacy while shortening development timelines.
Creative Biogene's Plant Genetic Transformation Platform leverages our innovative technology services platform, integrating end-to-end capabilities including gene editing, vector construction, transformation and regeneration, molecular characterization, and functional validation. We provide comprehensive services for plant research, molecular breeding, and industrial applications, covering the full workflow from gene/vector design to delivery of transgenic or edited materials.
Through advanced approaches such as multi-gene knockouts, base editing, prime editing, and targeted gene modifications, our platform supports C3/C4 model plants, major cereal crops, horticultural and economic crops, and oil crops, establishing a robust and versatile plant transformation system. We provide both modular services for research groups and deeply customized solutions, including project design, technical assessment, implementation, training, and follow-up data support.
Gene Editing System

At Creative Biogene, precision meets innovation. Our Gene Editing System harnesses CRISPR/Cas technologies, NHEJ-mediated mutations, and template-driven homologous recombination to deliver site-specific insertions and trait-optimized modifications.
Genetic Transformation System

Whether performing rapid transient assays or generating stable transgenic plants, this system bridges the gap between molecular constructs and real-world phenotypes, enabling efficient organ-specific transformation and seamless regeneration of fully developed plants, accelerating research and trait development.
High-throughput Genotyping System

Speed and accuracy converge in our High-throughput Genotyping System, designed for large-scale, precise genetic analysis. Creative Biogene provides rapid assessment of editing outcomes, allelic diversity, and off-target events.

Brassicaceae Family
Model and Cereal Plants
Fruits and Horticultural Crops
Industrial and Energy Crops
Leguminous Plants
Our platform is organized into five key modules, which can be used individually or combined into a complete workflow. Modules are flexible and customizable based on client needs.
Case Study 1
A study investigating the regulatory roles of intronic enhancers in Arabidopsis thaliana utilized Creative Biogene's pGreenII vector system to perform transient expression. Genome-wide prediction identified over 900 candidate intronic enhancers in seedlings and more than 1,200 in floral tissues. Functional validation was conducted using reporter constructs (pGreenII 0800-LUC) and effector vectors (pGreenII 62-SK) in Nicotiana benthamiana, demonstrating enhancer activity in 15 of 21 candidates. Further CRISPR/Cas-mediated deletions of three enhancers caused partial transcriptional repression and distinct developmental phenotypes.
Figure 1. Functional validation of SPL9 and EDT1 binding motifs in DHS7#1 and DHS7#2 enhancers through Y1H and luciferase assays. (Meng F, et al., 2021)
Case Study 2
A stable Oryza sativa mutant line (CCRM-2208) targeting OsTGA5/rTGA2.3 (Os01g0279900) was generated by Creative Biogene using CRISPR/Cas9-mediated genome editing. The binary vector pCB-35S-Cas9-OsU6-sgRNA-HygR was constructed and introduced into Agrobacterium tumefaciens strain EHA105 for transformation of embryogenic calli derived from the Japonica cultivar Nipponbare. The tga5 loss-of-function mutation was confirmed through next-generation sequencing of a 2.2 kb genomic region encompassing the sgRNA target site, with validation performed using Oxford Nanopore sequencing and custom annotation. After propagation, mutant and wild-type seeds were preserved under controlled temperature and humidity conditions for subsequent physiological and developmental studies.
Figure 2. OsTGA5 affects trait canalization. (Dunivant TS, et al., 2025)
Learn more about vector construction, plant transformation, molecular characterization, functional analysis, or RNA FISH services. Our technical team provides free project evaluation, technical recommendations, and preliminary quotes. Let's advance plant genome editing together.
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