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Single-Stranded DNA (ssDNA) Synthesis Service

Creative Biogene, as one of the leading biotechnology companies, can offer the dedicated service for the synthesis of high quality Single-Stranded DNA (ssDNA) to customers worldwide. Creative Biogene's sophisticated equipments, advanced technologies and highly experienced staffs are available to help you carry out your specific project as cost effectively and quickly as possible, without compromising on quality.

Single-Stranded DNA (ssDNA) Synthesis Service

Single-strand DNA (ssDNA) is considered an elemental material which can be used in numbers of biotechnology applications, including the scaffold for DNA nanotechnology, the donor DNA for clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein 9 (Cas9) systems CRISPR-Cas9 systems, carrier for drug delivery, in molecular diagnostic, DNA-based data storage, and various nanoscale applications. Although numerous methods have been developed to produce ssDNA, the production of ssDNA may become prohibitively expensive or onerous depending on the required size, scale and purity. Chemically synthesis is considered an economic method, but such ssDNA is limited beyond length of ~200nt and requires additional processing to remove impurities. Alternatively, production of single strands from a double-stranded DNA (dsDNA) template via enzymatic methods may be used, but is frequently limited by complexity of the protocols, scalability and/or purity of the recovered strands. In addition, these methods could not be used to synthesize ssDNA with the strands length up to 10k nt at high yield.

As one of the leading biotechnology companies, Creative Biogene is able to offer ssDNA synthesis service with sequence length up to 10k at micrograms scales using our unique and proprietary process. Creative Biogene has years of professional and abundant experience that can help customers synthesis ssDNA to meet your downstream needs. Creative Biogene has confident in providing you with the most affordable, high-quality service to ensure your satisfaction in a timely and professional manner. If you have any special requirements in our ssDNA synthesis service, please feel free to contact us. We are looking forward to working together with your attractive projects.

References:

  1. Hao M, et al, (2020). Current and Emerging Methods for the Synthesis of Single-Stranded DNA. Genes, 11(2), 116.
  2. Minev D, et al, (2019). Rapid in vitro production of single-stranded DNA. Nucleic acids research, 47(22), 11956-11962.
* For research use only. Not intended for any clinical use.
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