Creative Biogene is a leading biotechnology company in providing sgRNA library service for customers. Our sophisticated equipments, advanced technologies and highly experienced staffs are available to assist you in designing sgRNA constructs to target particular genes, synthesis oligos on arrays and clone the synthesized oligos into lentiviral vectors. With the help of highly experienced staffs, Creative Biogene can promise the fastest turnaround time than any other suppliers in the industry.
A single guide RNA (sgRNA, also known as guide RNA or gRNA) is a RNA sequence that can guide the Cas9 to the desired location of the cell’s genome.[1, 2, 3]With the continuous development of RNA technology, sgRNA library service is available now. Creative Biogene offers sgRNA libraries for high-throughput knockout of specific genes, which is a powerful tool for systematic genetic analysis in mammalian cells, facilitating gene discovery, genome-scale functional interrogation and drug discovery. With years of experience in research of CRISPR/Cas9 system, Creative Biogene can provide you with the best research materials and support in the CRISPR/Cas9 and sgRNA field.
Creative Biogene offers custom sgRNA library services for your scientific research as follows:
 Ledford H. CRISPR, the disruptor.Nature, 2015, 522(7554):20-4.
 Doench JG, Fusi N, Sullender M, et al. Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9. Nat Biotechnol. 2016, 34(2):184–191
 HendelA,BakRO,ClarkJT,et al.ChemicallymodifiedguideRNAs enhance CRISPR-Cas genome editing in human primary cells. Nature biotechnology, 2015