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Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cells that are derived from various somatic cells by introduction of sets of pluripotency-associated genes or reprogramming factors. The iPSC technology enables the development of any type of human cells. Tissues derived from iPSCs are nearly identical to the cell donor and thus can avoid immune system rejection. Thus, iPS cells are useful tools in drug development and transplantation medicine.
iPS cells can be generated by using a set of transcription factors or stem cell factors which include OCT3/4, SOX2, NANOG, LIN28, c-Myc, and KLF4. Recombinant virus particles are currently used for introduction of reprogramming factors into somatic cells to create iPSCs. The use of lentiviruses is a powerful laboratory tool in iPS technology. Creative Biogene provides prepackaged lentiviral particles to accelerate your progress in the generation of your own iPS cells. All our iPS lentiviral particles are well qualified and in high titers.
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Creative Biogene is a US-based manufacturer and provider of genomics and proteomics products and services for academic and governmental research institutes, pharmaceutical and biotechnology industry.