AI-Driven Gene Editing and Therapy

Creative Biogene is the world's leading provider of genetic research products and services, trusted by researchers in more than 40 countries to support more than 200 studies worldwide. Our CRISPR/Cas9 platform^CB provides comprehensive gene editing services and products.

Gene Editing Technology Challenges

The development of gene editing technology has made significant progress, but it still faces multiple challenges. The synergy between Cas proteins and sgRNA is key to gene editing, but the complexity and diversity of Cas proteins limits their complete characterization and tool development. gRNA design is crucial to editing efficiency and specificity. Traditional methods are limited by multiple factors and difficult to achieve precise design.

Innovative AI-Driven Gene Editing Services

The use of AI has enabled the ground-breaking advancement in genome editing, especially in CRISPR technology. Researchers can improve editing efficiency and accuracy by using AI models in conjunction with targeting scores and genomic context.

Creative Biogene is pleased to provide our most recent AI-powered gene editing solutions. By fusing state-of-the-art AI technology with our decades of gene editing knowledge, our platform does comprehensive genomic data analysis, painstakingly creates editing tools, and provides customized solutions for our customers.

Service Content

Innovative AI technologies are used by Creative Biogene to deliver complete solutions for gene editing and biotechnology research. We provide accurate sgRNA design, mRNA sequence optimization, Cas protein characterisation, transformation, and intelligent editing outcome prediction. To promote scientific innovation, we seek to address a variety of obstacles in gene editing and biotechnology, whether it be improving efficiency, specificity, or gene expression.

Cas Protein Characterization and Transformation

Cas proteins are essential in precise gene editing with sgRNA, but their complexity hampers full characterization. Our service employs deep learning to provide personalized gene editing solutions, identifying efficient tools tailored to customer needs through thorough Cas protein sequence analysis, effectively supporting gene editing research.

Intelligent Editing Result Prediction

Accurate prediction of editing results is crucial in gene editing. Traditional methods face limitations due to data volume and complexity. Our deep learning technology overcomes these obstacles by analyzing various factors, providing accurate and reliable editing result prediction services for our customers.

Intelligent sgRNA Design Service

Traditional sgRNA design methods often struggle with factors like sequence characteristics and targeting efficiency, hindering precise tool design in gene editing. Our intelligent sgRNA design service utilizes deep learning algorithms, integrating genomic data and biological knowledge to offer efficient and specific solutions.

siRNA Drug Sequence Design Service

Target biology and cellular complexity limit siRNA target accessibility, including shielding and RNA-binding proteins. Traditional algorithms lack predictive power. Our AI-driven siRNA drug design service combines machine learning to address these challenges. Advanced structural modeling predicts siRNA structures, reducing design failures.

Codon Optimization in Synthetic Biology

Codons influence various processes like transcription, translation, protein folding, and function, leading to diverse expression potentials. Our AI-based Codon Optimization service utilizes advanced deep learning algorithms to enhance protein expression levels and improve gene expression efficiency.

mRNA Sequence Optimization Service

mRNA sequence optimization is complex, facing challenges like inefficient delivery systems, immune response regulation, and RNA instability, hindering mRNA drug development. Our AI-based optimization service tackles these issues by simultaneously optimizing codon usage and RNA stability.

Advantages of Our AI-Driven Gene Editing and Therapy Service

Advanced AI Technology: Our platform leverages cutting-edge artificial intelligence (AI) technology, with the help of large models such as OpenCRISPR-1, to quickly and accurately analyze large amounts of genomic data.
Closed-Loop Dry and Wet Experiments: By closely integrating gene editing design with experimental verification, the experimental closed-loop system improves the credibility of editing results.
Personalized Editing Solutions: We understand that each project and client may have unique needs and goals. Therefore, we offer personalized editing solutions tailored to our clients' specific needs.
Risk Mitigation: By reducing off-target effects and ensuring precise modifications, we minimize the potential for unintended consequences, thereby improving the safety and efficacy of gene editing applications.
One-Stop Service: Our AI-driven gene editing service provides a one-stop solution, including consulting planning, AI design optimization, experimental execution, data analysis, optimization adjustments, reporting documentation, and ongoing support.

* For research use only. Not intended for any clinical use.

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