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The increasing use of lentiviral vectors (LVV) for cell and gene therapy has boosted the market demand for GMP lentivirus production. Creative Biogene, a leading partner in GMP lentivirus production, offers innovative solutions that cover the entire workflow of lentivirus production. We are committed to combining our extensive expertise with our advanced lentiviral production platform to provide superior services and products to help our global customers achieve breakthroughs in the development of gene modified cell therapy and in vivo gene therapy programs.
Creative Biogene has developed an applique production system and a suspension production system to manufacture lentiviral vectors using proprietary HEK293 and 293T production cell lines. Our flexible production capacity provides GMP lentivirus production from 2 L-200 L. We can currently perform second or third generation lentivirus packaging in HEK293 cells and our experienced scientists can provide the best solution for our clients' project development demands.
| Lentiviral Vector Production Platforms | Description |
| Adherent lentiviral transduction |
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| Suspension lentiviral transduction |
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Creative Biogene has built a robust platform to produce lentiviral vectors, using either patch or suspension cultures for lentivirus production. In addition, we offer cell banking, process development and basic quality control (QC), and suspension lentivirus production services to meet all your demands from preclinical to clinical stages, providing flexibility and the highest quality lentiviral vector production services.
Combining expertise in lentiviral transduction with available and scalable capacity ensures that we can provide a reliable solution throughout the entire process of your LVV production.
To ensure high product yields and efficiency, our lentiviral vector production platform utilizes disposable technology and optimized closed and semi-automated processes to deliver larger batches with greater consistency and reliability.
We offer a complete set of proven, optimized process manufacturing procedures to support GMP production. Strong development capabilities are readily available for upstream and downstream process improvements. In addition, analytical testing services are available, including carrier stability testing as well as safety and sterility testing.
Creative Biogene is committed to applying our expertise to provide you with the latest technology from a state-of-the-art facility for sterile production of lentiviral vectors that can expand your lentiviral gene therapy program into a patient-ready product. Our strong development capabilities and extensive experience can be customized to help you determine which process will best meet your individual demands. Please feel free to contact us if you have a need, and our experienced specialists will be happy to assist you.
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