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Endotoxin Detection & Removal Service

Creative Biogene is a leading biotechnology company which has the expertise in providing endotoxin detection & removal service and related products for customers worldwide. Creative Biogene's sophisticated equipments, advanced technologies and highly experienced staffs are available to provide you with the comprehensive endotoxin detection & removal service, including gel-clot test, turbidimetric assay, chromogenic measurement and endotoxin removal. Creative Biogene’s goal is to provide you with a reliable and accurate endotoxin test result and/or the endotoxin-free biological products to ensure your satisfaction in a timely and professional manner.

Endotoxin Detection and Removal

Endotoxin, also called lipopolysaccharide (LPS), is a major component of the outer layer of the cell wall in Gram-negative bacteria. Bacterial endotoxin is a potent stimulator of the mammalian immune system in vivo, and it may decrease tissue culture cell viability, inhibit transfection efficiency in vitro, causing false readings in cell-based assays, or it can cause side effects in host organisms such as endotoxin shock, tissue injury, and even death. However, free LPS are always present in an environment containing Gram-negative species due to the constantly synthesis process of LPS and the releasement of LPS from cell wall when cells die. This means that tests specifically designed to detect endotoxin/LPS are essential to demonstrate the safety of pharmaceutical and medical device products.

In terms of years’ professional experience in this field, Creative Biogene can provide you with the most affordable, high-quality endotoxin detection and removal service and related products to best match your various needs.

Advantages of our endotoxin detection and removal services:

  1. A variety of detection methods to meet individual client needs
  2. High accuracy and sensitivity
  3. Reduce endotoxin levels to 0.5 EU/µg or less
  4. Competitive prices
  5. Fast turnaround time


  1. Jaffer U., Wade RG. & Gourlay T. (2010). Cytokines in the systemic inflammatory response syndrome: a review. HSR proceedings in intensive care & cardiovascular anesthesia, 2(3), 161.

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