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Reporter Stable Cell Lines

Reporter Stable Cell Lines

As useful tools for scientific research, reporter stable cell lines are those cells involved in expression of reporter protein(s) which are engineered through integrating the reporter expression cassettes into cell genomes mediated by plasmid or lentivirus vectors. In the studies of life science and biotechnology, the commonly used reporter genes are visually identifiable including green fluorescent protein (GFP), red fluorescent protein (RFP), luciferase, secreted alkaline phosphatase (SEAP) etc.

According to the upstream regulator of the reporter gene, reporter cell lines can be further divided into two groups: 1) Constitutive Reporter Cell Lines in which reporters are constitutively expressed under the control of a constitutive, strong promoter such as CMV promoter; and 2) Inducible Reporter Cell Lines in which reporters are inducibly expressed under the control of a minimal promoter fused to multiple inducer response elements.

Based on years of experience and in-depth investigation, scientists at Creative Biogene have established a large number of stable reporter cells in many popular cell lines suitable for multiple applications.

Constitutive Reporter Cell Lines

Inducible Reporter Cell Lines

Table 1. Frequently Requested - Constitutive Reporter Cell Lines

CategoryReporterHost Cell
Fluorescent ReporterGFP143 B, 324, 4T1, 9L, A375, A498, A549, AGS, Anip 973, ASPC -1, B16F0, B16 F10, Boy, BT 474, BV2, Bx Pc3, Ca761, CAOV3, Capan-1, Capan-2, CHO-K1, CNE2Z, colo205, Colon 38, COS-7, CT-26, DAOY, DU145, EKVX, FaDu, FEMX I, Flo-1, H460, H69, HCC70, HCT-116, HCT-15, HCT-8, HEK293, HEK293T, HeLa, Hep2, Hep 3B, HEP-G2, HGC27, HOP-62, HT 1080, HT-29, HTB 9, Huh-7, JURKAT, K562, KM-12, KM 28 BM, KU-7, LL/2, LnCap, LOXMIVI, LS 174, Ls180, L-SLM, MCF7, MDA-MB-231, MDA-MB-435, MDA-MB-435 2C5, MDA-MB-435 4A4, MDA-MB-453, MDA-MB-468, MDCK, Mel526, MIA-Paca 2, MMT 060562, MOLM13, MSTO-211H, MV3, N87, NALM6, NCI-H1299, NCIH1437, NCI-H1975, NCI-H661, NCI-N87, NIH3T3, NUGC 4, OPM2, OST, OVCAR-3, OVCAR-8, PaCa28, Panc-1, Pan02, PC-3, PC-12, R40LN, RGMI#186, RPMI8226, SH-SY5Y, SK-BR-3, SK-Hep-1, SK-LU-1, Sk-mel-5, SK-OV-3, SL4, SN12C, SNB-19, SOSN2, SW1116, SW480, SW620, SCC-25, T24T, T47D, TOV21, U2OS, U87 MG, U937, UACC257, UM-UC-3, UM-UC 14, Vcap, WiDr, XPAI
RFP143 B, 4T1, A375, A549, ASPC-1, B16F0, B16-F10, Bx Pc3, BV2, CEM, CHO-K1, CNE2Z, Colon 38, Colo26, CT26.WT, Dunning3327, DAOY, FEMX I, FaDu, FG A-12, H9C2(2-1), HCT-116, HCT-8, HEK293, HEK293T, Hep2, Hep 3B, Hep G2, HGC27, HMMG/HOS, HT 1080, HT29, Huh-7, KAK-1, LnCap, LOXMIVI, LL/2 H460, MDA-MB-231, MDA-MB-435 4A4, MDA-MB-435 2C5, MDA-MB-468, Mel526, MGC803, MIA-Paca 2, MMT 060562, MSTO-211H, MV3, MX-1, NCI-H1299, NCIH1568, NCIH1975, NIH3T3, NPA, NUGC 4, OVCAR-3, OVCAR-5, OVCAR-8, OST, Pan02, PC-3, R40LN, R90L, R90P, SK-BR-3, SW1116, SW480, SL4, SN12C, SOSN2, SH-SY5Y, SK-Hep-1, Sk-mel-5, T24T, T47D, TOV21, U14, U2OS, U87 MG, UM-UC 14, XPAI
GFP + RFP143 B, B16 F10, DU145, H460, HCT-116, HT 1080, Lewis Lung, MDA-MB-435, MDA-MB-231, MIA-Paca 2, MMT 060562, MV3, PC3, U87 MG, XPAI
Luciferase ReporterLuciferase4T1, A375, A549, B16F10, CT26.WT, HCT116, HT1080, LL/2, MCF-7, MDA-MB-231, SKOV-3
Dual ReporterGFP + LuciferaseAGS, HCC70, HT-29, MCF7, NCI-H1299, NCI-H1975, NCI-H661, NCI-N87
RFP + LuciferaseA549, CNE2Z, GBC-SD, H9C2(2-1), HCT-8, HEK293T, Hep3B, HepG2, HOS, Huh7, Li-7, MDA-MB-231, NCI-H1299, PLC/PRF/5, RBE, SK-HEP-1

Table 2. Frequently Requested - Inducible Reporter Cell Lines

CategoryReporterCo-expression FactorHost Cell
ATF6 PathwayLuciferase--CHO
AP1 PathwayLuciferase--HEK293T, HeLa
Androgen Receptor(AR) PathwayLuciferase--MDA-MB-453
BMP PathwayLuciferase--HEK293
CHOP PathwayLuciferase--CHO
CREB PathwayLuciferase--CHO, HEK293, NIH3T3
ELK1 PathwayLuciferase--HeLa, HEK293
Estrogen Receptor(ER) PathwayLuciferase--T47D
HIF PathwayLuciferase--Cos-7, HeLa, Neuro2a, NIH3T3
GFP--Ca761, MCF7, MDA-MB-231
IFN-α PathwayLuciferase--HeLa
IL6 PathwayLuciferase--HEK293
IRF PathwayLuciferase--HEK293, HepG2
NFAT PathwayLuciferase--HeLa, Jurkat T, K562, NIH3T3
NF-kB PathwaySEAPTLR2, TLR3, TLR4, TLR7, TLR8, TLR9, TLR10, TLR13, mTLR11, mTLR12HEK293
SEAP--HEK293, RAW264.7
Luciferase--A549, C2C12, HeLa, HEK293, HepG2, Jurkat T, MCF-7, MDA-MB-231, MEF, Neuro2a, NIH3T3
NRF2 PathwayLuciferase--HEK293, HepG2, MCF7, NIH3T3
p53 PathwayLuciferase--HeLa, RKO
SMAD PathwayLuciferase--HepG2, NIH3T3
SRF PathwayLuciferase--HeLa
STAT PathwayLuciferase--HeLa
Wnt PathwayLuciferase--CHO, HEK293, HEK293T, HeLa


  1. Analysis of gene expression and regulation
  2. In vivo and in vitro imaging studies
  3. Evaluation the development of tumor or cancer
  4. Monitoring the activation of intracellular signaling pathways induced by microbial molecules or cytokines
  5. Studying the interactions among receptors, ligands and agonists
  6. Functional genomics research and drug discovery


  1. Creative Biogene provides a large choice of reporter cell lines.
  2. All reporter cell lines provided by Creative Biogene are guaranteed free of mycoplasma contamination.
  3. If you could not find a reporter cell line of interest, our scientists can also tailor a reporter cell line based on your request.

Reporter Stable Cell Lines Products List

Frequently Asked Questions about Creative Biogene - Reporter Stable Cell Lines

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