Transcription Factors

Transcription factors sit at the core of immune regulation, translating extracellular signals into gene expression programs that define immune cell fate, activation, and functional plasticity. Our recombinant transcription factor proteins are developed as research-grade molecular tools, enabling controlled interrogation of immune signaling pathways across basic, translational, and early drug discovery studies.

Rather than focusing on isolated protein mechanisms, this product line is designed to support application-driven immunology research, where consistency, purity, and biological relevance are essential.

Transcription Factors in Immune Regulation

In immune cells, transcription factors function as convergence points for cytokine signaling, receptor activation, and environmental cues. They govern:

Immune cell differentiation and lineage commitment
Cytokine-responsive gene expression programs
Activation, exhaustion, and immune tolerance states
Crosstalk between inflammatory, hormonal, and metabolic signals

Recombinant transcription factor proteins provide defined, controllable reagents for dissecting these processes in vitro and in cell-based experimental systems.

Application-Oriented Use in Immunology Research

Our transcription factor protein portfolio is widely applied in:

Immune Signaling Pathway Studies

Supporting mechanistic studies of cytokine-driven and receptor-mediated signaling cascades relevant to inflammation, immune suppression, and immune activation.

Gene Regulation and Transcriptional Control Assays

Used in DNA-binding studies, transcriptional regulation models, and functional assays examining immune gene expression dynamics.

Immune Cell Function & Plasticity Research

Facilitating studies in T cells, macrophages, dendritic cells, and other immune populations where transcriptional programs define phenotype and response.

Immuno-Oncology and Immune Dysregulation Models

Enabling exploration of transcriptional regulators involved in immune escape, chronic inflammation, and immune-mediated disease states.

Broad Coverage Across Key Transcription Factor Classes

This product line includes recombinant proteins representing multiple transcription factor families relevant to immune biology, such as:

Immediate early response transcription factors
Cytokine-activated signal transducers
Nuclear receptor-associated transcription regulators

Rather than isolated products, the portfolio is curated to support pathway-level and system-level immunology research, allowing researchers to select tools aligned with their experimental context.

Protein Quality Built for Reproducible Research

All transcription factor recombinant proteins are produced under a standardized and controlled manufacturing framework, ensuring suitability for sensitive immunological assays:

Recombinant expression in well-characterized systems
High-purity protein preparation validated by orthogonal analytical methods
Low endotoxin levels compatible with immune cell–related studies
Lot-to-lot consistency to support reproducibility and longitudinal projects

Each protein is supplied in a research-ready, lyophilized format, enabling flexible experimental design and long-term storage.

Available Recombinant Proteins

Explore Available Transcription Factor Proteins

Browse our current portfolio of recombinant transcription factor proteins to identify tools aligned with your immunology research focus.

For custom formats, related signaling proteins, or project-specific needs, technical support is available upon request.

Cat.No.	Product Name	Price
RP00147	Recombinant Human EGR1 (N-6His)	Inquiry
RP00195	Recombinant Human STAT3 (C-6His)	Inquiry
RP00588	Recombinant Human ESR1 (N-6His)	Inquiry

* For research use only. Not intended for any clinical use.

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