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Functional Proteins

Immune regulation relies not only on receptors and cytokines, but also on a diverse set of enzymes and functional proteins that shape signaling cascades, extracellular environments, and downstream biological outcomes.

This product category brings together immune-related enzymes and regulatory proteins that play essential roles in complement activation, nucleotide metabolism, coagulation control, intracellular signaling, and disease-associated pathways.

Functional Proteins Beyond Classical Enzyme Categories

Many biologically important proteins do not fall neatly into a single enzyme class. Instead, they function at the intersection of:

  • Enzymatic activity and immune regulation
  • Proteolytic processing and inflammatory control
  • Structural or membrane-associated roles linked to immune activation

Key Research Areas Supported

Complement System and Innate Immunity

Recombinant complement-related proteins enable mechanistic studies of complement activation, regulation, and immune surveillance, supporting research in inflammation, host defense, and immune-mediated diseases.

Enzymatic Regulation of Immune Signaling

Enzymes involved in nucleotide metabolism, proteolysis, and extracellular substrate processing provide insight into immune cell activation thresholds and signaling modulation.

Cellular Stress, Trafficking, and Signaling Pathways

Membrane-associated and intracellular functional proteins support studies of lysosomal trafficking, transcriptional regulation, and stress-responsive pathways in immune and non-immune contexts.

Disease Mechanisms and Translational Research

Select proteins in this category are widely used in disease-related research, including neurodegeneration, coagulation disorders, and immune dysregulation.

Representative Functional Protein Classes

This category includes recombinant proteins spanning multiple functional classes, such as:

  • Complement factors and regulators
  • Ectonucleotidases and phosphodiesterases
  • Proteases and carboxypeptidases
  • Lysosome-associated membrane proteins
  • Intracellular signaling and transcription-related proteins

Products are available across human, mouse, and non-human primate species, supporting translational and comparative studies.

Flexible Formats for Diverse Assay Needs

To accommodate different experimental designs, proteins are offered in multiple formats, including:

  • His-tagged recombinant proteins
  • Fc fusion proteins for binding and functional assays
  • Biotinylated proteins for interaction studies
  • Tag-free proteins for enzymatic activity evaluation

These formats integrate readily into biochemical, cell-based, and immunological assay systems.

Production and Quality Considerations

Proteins are produced using mammalian or bacterial expression systems, selected based on structural and functional requirements. Each product undergoes standardized quality control to ensure:

  • High purity and structural integrity
  • Consistent lot-to-lot performance
  • Suitability for immune and enzymatic assays

Available Recombinant Proteins

Explore Immune-Related Enzymes & Functional Proteins

Browse the full selection of recombinant immune-related enzymes and functional proteins to identify tools suited to your research objectives. Custom species variants, tags, and related proteins are available upon request.

* For research use only. Not intended for any clinical use.
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