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GFP Reporter Cell Line-HT1080

For research use only. Not intended for any clinical use.
Cat.No.
CSC-RR0271
Description
GFP Reporter Cell Line-HT1080 is engineered to stably overexpress GFP reporter gene. It is an ideal positive control for use in fluorescence assays. In addition, HT1080 cells form tumors post implantation into immunocompromised mice. The in vivo growth of these tumors can be monitored using optical imaging.
Host Cell
HT1080
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry ice
Stability
Validated for at least 10 passages
Storage
Liquid nitrogen

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HT1080 cells are human fibrosarcoma cells derived from the epithelial cells of a 35-year-old male fibrosarcoma patient's connective tissue, harboring an activated N-ras oncogene. These cells are sensitive to human poliovirus, cat RD-114 virus, feline leukemia virus, and herpes simplex virus. HT1080 cells have a chromosome modal number of 46, with a range of variability between 44 and 48. They are suitable for 3D cell culture, bioproduct manufacturing, scientific research, and serve as an appropriate host for transfection. The GFP reporter cell line HT1080 HT-1080 is engineered to express a green fluorescent protein (GFP) reporter gene, serving as a valuable tool for various cellular studies. HT1080, also known as fibrosarcoma cell line, originates from a human fibrosarcoma tumor and has been extensively utilized in cancer research.
1. Cancer Research: HT1080 cells are a human fibrosarcoma cell line with an activated N-ras oncogene and are sensitive to a variety of viruses. These cells can be used to study aspects such as tumor biology, tumor microenvironment, and drug treatment strategies. 2. Cell Culture Technology: HT1080 cells are suitable for 3D cell culture and bioproduct manufacturing, and can be used for bioengineering and drug screening. 3. Transfected Host: Since HT1080 cells are easy to transfect, they can serve as an ideal host for studies such as gene editing, gene transfer, and drug delivery. 4. GFP Reporter Gene: Through engineering, HT1080 cells express the green fluorescent protein (GFP) reporter gene, which can be used to monitor biological processes such as gene expression, cell migration, and cell proliferation in real time. 5. Disease Modeling: HT1080 cells can be used to establish disease models to study disease mechanisms, diagnostic methods, and potential treatment strategies.
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