Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
CRDMO Services for Viral Vector & Protein Production
Creative Biogene provides end-to-end contract research, development, and manufacturing (CRDMO) services built on a foundation of intellectual property clarity and technical excellence. Our formal, worldwide commercial license from AdVec™ Inc. for the HEK293 cell line family ensures your viral vector, vaccine, or therapeutic protein project begins and ends with complete legal and commercial freedom.
The HEK293 cell line is the gold standard for transient and stable expression, renowned for its high transfection efficiency, robust growth, and ability to produce complex proteins and viral vectors with proper post-translational modifications.
We hold an active, global non-exclusive commercial license from AdVec™ Inc., the recognized IP holder, granting us the rights to use the proprietary HEK293 cell line and its derivatives for both research and commercial applications.
Freedom to Operate
Your project utilizes a cell platform with cleared underlying IP, mitigating a critical legal risk for product commercialization.
Direct from the Source
Our license originates from the laboratory of Dr. Frank L. Graham, co-creator of the HEK293 cell lines, ensuring authenticity.
Commercial Rights Included
The license covers the commercial use of biological materials (viruses, vectors, proteins) produced using the licensed HEK293 cells.
Leveraging our licensed HEK293 and adapted suspension (e.g., 293N3S) cell lines, we offer comprehensive development and manufacturing services.

Viral Vector Manufacturing

Recombinant Protein & Antibody Expression

Cell Line Services & Licensing Support
Combining Legitimacy with Expertise
| Key Differentiator | What It Means for Your Project |
|---|---|
| Validated Legal Foundation | Our direct license from AdVec™ provides IP certainty for the core production platform, securing your commercialization path. |
| End-to-End Solutions | From cell banking and process development to analytical testing, scale-up, and cGMP manufacturing. |
| Platform Expertise | Deep experience in HEK293 culture optimization, transfection, and downstream processing to maximize titers and quality. |
| Quality & Compliance | Development aligned with ICH Q7, Q8, Q9, Q10, and Q11 principles, supported by robust quality systems for clinical and commercial supply. |
| Confidential Collaboration | Protection of your IP is paramount, governed by strict confidentiality agreements and secure data management. |
Consultation
We discuss your molecule, goals, and timeline.
Proposal
We provide a tailored technical and commercial proposal based on our licensed platform.
Agreement
We align on scope, deliverables, and terms.
Execution
Our dedicated team executes the project with transparent communication.
Delivery
We supply high-quality materials and comprehensive documentation.
Footer Note:
Services described are offered under our executed License Agreement with AdVec™ Inc. Clients are responsible for ensuring the compliance of their specific products with all other applicable intellectual property rights. "AdVec" and related marks are trademarks of AdVec™ Inc.