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Plasmid DNA Production Service

Creative Biogene is a biotechnology company specializing in custom plasmid DNA production service. With years of experience in service of plasmid DNA production, Creative Biogene can offer customized plasmid services at scales from micrograms to grams using Creative Biogene’s unique and proprietary process. Besides, Creative Biogene can provide you with multiple quality grades’ plasmids, including research grade, endo-toxin free grade and GMP grade plasmid DNAs. Creative Biogene’s goal is to provide you with the most affordable, high-quality plasmid DNA manufacturing services to ensure your satisfaction in a timely and professional manner.

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Plasmids are small DNA molecules that are physically separated from the chromosomal DNA and can replicate independently. They are most commonly found in bacteria as small circular, double-stranded DNA molecules [1, 2]. Nowadays, plasmid DNAs serve as important tools in genetic engineering. They are commonly used in genetics and biotechnology labs, where they are used to clone and amplify (make many copies of) or express particular genes [3]. Creative Biogene can provide you with high-quality plasmid DNA production services. You can select scales and quality grades of production to best match your specific needs.

Creative Biogene can provide you with multiple quality grades’ plasmids. You can select the grade of production to best match your needs.

  1. Research grade – For typical molecular biology research, including re-cloning, sequencing, PCR and protein manufacturing
  2. Endo-toxin free grade – Recommended for effective cell transfection, gene vaccine and protein manufacturing and animal studies
  3. GMP grade – The GMP grade plasmid DNA can be used for DNA vaccines, gene therapy, or ex-vivo applications.

Creative Biogene offers custom plasmid DNA production services for your scientific research as follows:

  1. Selection of host strain and growth conditions.
  2. High-cell-density fermentation.
  3. Cell harvesting, lysis and plasmid purification.
  4. Wide range of quality control testing including genomic DNA /RNA /protein contamination test, endotoxin (lipopolysaccharides) assay, restriction profile analysis, DNA sequencing , OD260/280 readings and so on.


  1. Lipps G (editor). Plasmids: current research and future trends. Caister Academic published, 2008.
  2. Lederberg J. Cell genetics and hereditary symbiosis. Physiol. Rev. 1952, 32 (4): 403 – 430.
  3. Russell, David W. Sambrook, Joseph. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory published. 2001.

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