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mRNA Synthesis

mRNA Synthesis

Synthetic mRNA has recently come into focus as a potential new drug class to deliver genetic information. Such synthetic mRNA can be engineered to transiently express proteins more rapidly and safety, due to no need of transnuclear localization and lack of integration into host cell genome. In addition, the development of in vitro transcription (IVT) technique renders the easy modulation of mRNA's biochemical properties. Throughout the IVT process, various modified nucleotides, for example 5-methylcytidine, 5-methoxyuridine and pseudouridine can be simply incorporated into the synthetic mRNA. Depending on the properties of chemically-modified nucleotides, the immunogenicity or stability of the resulting mRNA can be improved. Therefore, the synthetic mRNA has become much popular among a broad range of potential applications, such as regenerative medicine, basic cell biology, treatment of diseases, and reprogramming of cells.

Creative Biogene, as one of the leading biotechnology companies, can provide a variety of high-quality kits and raw materials for customers worldwide to help your mRNA synthesis.

* For research use only. Not intended for any clinical use.
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