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-The application of PV-based delivery systems in tumor immunotherapy
PV systems are known to be capable of content material delivery to specific host cells through their only round of replication. Therefore, when packaged with 'suicide genes' dictating for tumor cell death, it becomes a powerful weapon against malignancies that could be difficult for conventional drug administration, for example cancers in mucosal tissues. The efficacy of PV-based suicide gene delivery has been demonstrated by research on treatment of bladder cancer. In this application, artificially assembled PVs act as delivery vectors transferring suicide genes to the internal of tumor cells. Successful induction of tumor cell death (TCD) and further adaptive immune response against NIMBC has been achieved on immunotherapy using PV vectors packaged in Human Papillomavirus (HPV) capsids.
Fig 1. Mechanisms of PVs delivering their content (Rohovie, Nagasawa, & Swartz, 2016).
-The advantage of PV-mediated systems to conventional approaches?
-What is offered by Creatvie Biogene?
We also offer fully customized solutions should your research requires specific items/services that have not been included. For any inquiries, please feel free to contact us at email: email@example.com, our highly experienced technical support scientists are more than happy to discuss over details of your research plan and offer the best solution catered specifically to your needs.
-Why Creative Biogene?
Creative Biogene has rich history of success and commitment to providing our clients with the best service using only state-of-the-art equipment and finest materials. Coming from world renowned institutions around the globe, researchers of our laboratory team are well-trained and highly experienced with the devotion and dedication to fulfill any requirements by our clients to satisfactory. At Creative Biogene, industry-leading PV customization service is offered to all of our clients at competitive pricing with rapid turnaround time, ensuring an easy and trouble-free start of your research.
Creative Biogene is a US-based manufacturer and provider of genomics and proteomics products and services for academic and governmental research institutes, pharmaceutical and biotechnology industry.