Wheat Transformation Service

Introduction

Creative Biogene offers wheat one-stop solution including genetic transformation, genome editing and genetic improvement. Whether your goal is disease resistance, climate adaptability, or market-driven trait enhancement, we deliver tailored, efficient, and scientifically robust solutions. Our services empower breeders, researchers, and agribusinesses to reimagine wheat for the 21st century.

Wheat (Triticum aestivum), a vital staple feeding over 35% of the global population, faces unprecedented challenges from climate volatility, soil degradation, and evolving pathogens. Traditional breeding alone cannot keep pace with these demands. Genetic transformation and precision genome editing are now indispensable for developing resilient, high-yielding wheat varieties tailored to modern agriculture.

Services offered by Creative Biogene

Wheat's hexaploid genome (AABBDD) poses unique challenges. We specialize in overcoming polyploidy barriers to deliver precise, scalable outcomes.

Cutting-Edge Transformation Platforms

High-Efficiency Stable Transformation: Agrobacterium-mediated and biolistic methods optimized for elite and recalcitrant wheat cultivars. Embryogenic callus and immature embryo systems for robust regeneration.
Transient Transformation: Rapid gene silencing/overexpression in protoplast and callus system for pre-editing validation.
Haploid Induction: Accelerate breeding via doubled haploid technology combined with genome editing.

Next-Generation Genome Editing

Multiplex Genome Editing: Knock out redundant genes across subgenomes (e.g., A, B, D) to enhance traits like gluten quality or pathogen resistance.
Base Editing: Introduce point mutations (e.g., herbicide tolerance in AHAS genes) without double-strand breaks.
Prime Editing: Achieve targeted insertions or deletions (e.g., GW2 gene for larger grain size) without donor templates.
Transgene-Free RNPs: Deliver ribonucleoproteins to generate non-GMO edited lines, ideal for regulatory-friendly commercialization.

Trait Development Pipeline

Enhanced Stress Tolerance: Overexpress DREB genes for drought resilience or HSPs for thermotolerance.
Disease Resistance: Edit susceptibility genes (e.g., TaLr34) to combat fungal and viral infections.
Yield Boosters: Optimize tillering (TB1), grain size (TaGW2), and nitrogen-use efficiency (TaNRT).
Nutritional Upgrades: Increase iron bioavailability via NAS gene editing or reduce phytic acid for improved mineral absorption.
Quality Traits: Modify glutenin profiles for baking quality or reduce allergens like alpha-amylase/trypsin inhibitors.

Advantages

Fully matured plant genetic engineering platform.
Professional teams in molecular construction, tissue culture, transformation and phenotypic analysis.
Years of experience in crop genome editing, base editor, and prime editor.
Fast turnaround time and affordable price

Case Study

Figure 1. Agrobacterium-mediated wheat transformation (Bob white)

Experienced scientists and experts of Creative Biogene will work closely with you to make sure your project is given the best intellectual and technical support. For more information of service details, questions or collaborations, please feel free to contact us.

* For research use only. Not intended for any clinical use.

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