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Kinases serve as key regulatory molecules for most cellular pathways, which are often associated with diseases: as causative agents for diseases, especially many cancers, or as targets for drug development.
The reporter cell lines have shown great potential for cell tracing, drug development and gene function studies, etc. Creative Biogene offers reporter cell lines with high sensitivity and accurate localization, which have become a powerful tool of choice for researchers.
Immune checkpoints are the crucial regulators of immune system and play essential roles in maintaining self-tolerance, preventing autoimmune responses, and minimizing tissue damage by regulating the duration and intensity of the immune response.
Biological therapeutics and diagnostics (theranostics) are rapidly growing products in the pharmaceutical market. They include various monoclonal antibodies (mAbs), vaccines, hormones, and other proteins, all of which have wide range of applications. Biotherapeutic proteins represent a mainstay of treatment for a multitude of conditions, for example, autoimmune disorders, hematologic disorders, hormonal dysregulation, cancers, infectious diseases and genetic disorders.
Increasing availability of genomic and transcriptomic resources for industrially important cell lines coupled with advances in genome editing technology have opened new avenues for cell line development. These developments are poised to help biosimilar manufacturing, which requires targeting pre-defined product quality attributes, e.g., glycoform, to match the innovator's range.
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