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Panoply™ Human TLR8 Knockdown Stable Cell Line

Cat.No.
CSC-DC016007
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
TLR8
Synonyms
TLR8; toll-like receptor 8; CD288; MGC119599; MGC119600;
Gene ID
UniProt ID
Q9NR97
mRNA Refseq
BC101075
Chromosome Location
Xp22
Function
DNA binding; RNA binding; double-stranded RNA binding; receptor activity; single-stranded RNA binding;
Pathway
Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88 dependent cascade initiated on endosome, organism-specific biosystem; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling, organism-specific biosystem; TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation, organism-specific biosystem; Toll Like Receptor 7/8 (TLR7/8) Cascade, organism-specific biosystem; Toll Like Receptor 9 (TLR9) Cascade, organism-specific biosystem;
MIM

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