shRNA set against Mouse TLR8 (NM_133212.2)

Name: shRNA set against Mouse TLR8 (NM_133212.2)
SKU: SHH428036
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH428036

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Product Information

Gene Information

Cat. No.	SHH428036
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	TLR8
Gene Name	Tlr8 toll-like receptor 8 [ Mus musculus ]
Species	Mouse
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	Tlr8 toll-like receptor 8 [ Mus musculus ]
Gene Symbol	Tlr8
Gene Description	toll-like receptor 8
GeneID	170744
Uni ProtID	P58682
mRNA Refseq	NM_133212.2
Protein Refseq	NP_573475.2
Chromosome Location	X F5; X
Function	DNA binding; double-stranded RNA binding; single-stranded RNA binding;
Pathway	Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88 dependent cascade initiated on endosome, organism-specific biosystem; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling, organism-specific biosystem; TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation, organism-specific biosystem; Toll Like Receptor 7/8 (TLR7/8) Cascade, organism-specific biosystem; Toll Like Receptor 9 (TLR9) Cascade, organism-specific biosystem;

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