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Rat Tlr8 ORF Clone(NM_001101009.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR372457

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Gene Information

Cat. No. CDCR372457
Product Type ORF Clone
Gene Abbr Tlr8
Species Rat
Tag C-terminal Myc-DDK
ORF Size 3090 bp
Vector pCMV6-Entry
Target Gene TLR8
Background The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008]
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