shRNA set against Human TLR8 (NM_138636.4)

Name: shRNA set against Human TLR8 (NM_138636.4)
SKU: SHH428032
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH428032

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Product Information

Gene Information

Cat. No.	SHH428032
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	TLR8
Gene Name	TLR8 toll-like receptor 8 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	TLR8 toll-like receptor 8 [ Homo sapiens ]
Gene Symbol	TLR8
Synonyms	TLR8; toll-like receptor 8; CD288; MGC119599; MGC119600;
GeneID	51311
Uni ProtID	Q9NR97
mRNA Refseq	BC101075
Chromosome Location	Xp22
Function	DNA binding; RNA binding; double-stranded RNA binding; receptor activity; single-stranded RNA binding;
Pathway	Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88 dependent cascade initiated on endosome, organism-specific biosystem; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling, organism-specific biosystem; TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation, organism-specific biosystem; Toll Like Receptor 7/8 (TLR7/8) Cascade, organism-specific biosystem; Toll Like Receptor 9 (TLR9) Cascade, organism-specific biosystem;
MIM	300366

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