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Human TACR3-tGFP Stable Cell Line-SHSY5Y

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Cat.No.
CSC-RG0030
Background
Neurokinin 3 receptor is the gene that encodes a protein that is one of the three Neurokinin receptors (NKRs), also termed as TACRs. The Neurokinin receptor family is a group of Gcoupled receptors whose principal ligands are the Neurokinins. This protein family encompasses a wide range of functions including various parachine, autocrine and endocrine processes. NK3 receptors are distributed widely throughout the CNS, and are found in high levels in the cerebral cortex, basal ganglia and dorsal horn of the spinal chord. They have a limited distribution in peripheral tissues, and are found in ganglia (e.g., myenteric plexus), kidney, and in a limited number of smooth muscles (e.g., rat portal vein). NK3 antagonist has been proposed as antipsychotics.
Growth Properties
Mixed, adherent and suspension
Morphology
Epithelial
Host Cell
SHSY5Y
Ship
Dry ice
Gene Information
Official Symbol
TACR3
Synonyms
TACR3; tachykinin receptor 3; neuromedin-K receptor; neurokinin beta receptor; NK3R; NK-3 receptor; neurokinin B receptor; NKR; NK-3R; TAC3RL; MGC148060; MGC148061;
Gene ID
MIM
UniProt ID
P29371
Chromosome Location
4q25
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
Function
G-protein coupled receptor activity; receptor activity; signal transducer activity; tachykinin receptor activity;

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