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Human BDKRB1 Stable Cell Line-HEK293

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Cat.No.
CSC-RG0002
Background
BDKRB1 gene encodes a protein that is one of two Bradykinin receptors. The bradykinin receptor family is a group of G-protein coupled receptors whose principal ligand is the protein bradykinin. This gene encodes a receptor for bradykinin B1. Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
BDKRB1
Synonyms
BDKRB1; bradykinin receptor B1; B1 bradykinin receptor; B1BKR; BKR1; bradyb1; BK-1 receptor; bradykinin receptor 1; bradykinin B1 receptor; B1R; BKB1R; BRADYB1;
Gene ID
MIM
UniProt ID
P46663
Chromosome Location
14q32.1-q32.2
Pathway
ACE Inhibitor Pathway, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem;
Function
G-protein coupled receptor activity; bradykinin receptor activity; peptide binding; receptor activity; signal transducer activity;

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