Small-Scale Production
Small-scale manufacturing is often the first step in the development and production of biologics projects. Creative Biogene uses our extensive experience and knowledge in the industry to provide our clients with specialized small-scale manufacturing services to ensure that their final products are produced in an efficient and cost-effective manner.

Introduction of Small-Scale Production Services
Small-scale production refers to the manufacture of biological products, such as recombinant proteins, antibodies, vaccines and cellular therapies, on a smaller scale than large-scale production, with the aim of establishing and optimizing the production process. Small-scale production is typically used for early-stage development and optimization, feasibility studies, proof-of-concept studies, preclinical volume production and testing, and manufacturing for clinical trials. In small-scale production, the manufacturing process is designed to produce a limited amount of product, usually a few hundred milliliters to a few liters.
Benefits of Small-Scale Production
Small-scale production is essential for the development of biologics. Creative Biogene provides efficient small-scale production services to help customers save time and cost in subsequent scale-up production. Our services are designed to help you get valuable information in the following series of processes:
- Test early-stage processes and optimize them before proceeding to mass production.
- Conduct feasibility studies to assess the potential of new products and determine the best production process.
- Generate preclinical batches to be tested in animal models.
- Produce sufficient quantities of clinical trial materials for use in human trials to determine safety, efficacy, and dose levels.
- Save costs, reduce waste, and accelerate product development and time-to-market.
The Main Tasks of the Small-Scale Phase
- Process: reaction parameters, process post-treatment methods.
- Materials: material properties, material control.
- Quality and safety testing.
Why Choose Creative Biogene?
- Extensive experience and expertise in biotechnology and bioengineering.
- Small-scale bioreactors for culturing and growing cells for the production of biologics, with volumes ranging from a few milliliters to several liters.
- A variety of analytical methods are used to test biologics for purity, potency and safety, including HPLC, ELISA and mass spectrometry.
- The production complies with regulatory requirements for quality control and safety.
Creative Biogene offers small-scale production services that allow us to optimize your process and remove potential manufacturing hurdles before moving to larger scale production. Please feel free to contact us if you have a need, and our experienced specialists will be happy to assist you.
* For research use only. Not intended for any clinical use.