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Panoply™ Human ORC4 Knockdown Stable Cell Line

Cat.No.
CSC-DC011126
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
ORC4
Synonyms
ORC4L; ORC4P
Gene ID
UniProt ID
O43929
mRNA Refseq
Protein Refseq
Chromosome Location
2q22-q23
Function
ATP binding; DNA replication origin binding; nucleoside-triphosphatase activity; nucleotide binding; protein binding;
Pathway
Activation of ATR in response to replication stress, organism-specific biosystem; Activation of the pre-replicative complex, organism-specific biosystem; Assembly of the ORC complex at the origin of replication, organism-specific biosystem; Assembly of the pre-replicative complex, organism-specific biosystem; Association of licensing factors with the pre-replicative complex, organism-specific biosystem; CDC6 association with the ORC:origin complex, organism-specific biosystem; CDT1 association with the CDC6:ORC:origin complex, organism-specific biosystem;
MIM

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