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Human PARP2 Knockdown Cell Line-HeLa

See other products for PARP2
Cat.No.
CSC-RK0019
Background
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HeLa
Ship
Dry ice
Gene Information
Official Symbol
PARP2
Synonyms
PARP2; poly (ADP-ribose) polymerase 2; ADP ribosyltransferase (NAD+; poly(ADP ribose) polymerase) like 2 , ADPRTL2, poly (ADP ribose) polymerase family, member 2; poly [ADP-ribose] polymerase 2; ADPRT-2; hPARP-2; poly(ADP-ribose) synthetase; poly[ADP-ribose] synthase 2; poly[ADP-ribose] synthetase 2; NAD(+) ADP-ribosyltransferase 2; poly (ADP-ribosyl) transferase-like 2; poly (ADP-ribose) polymerase family, member 2; ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2; ADPRT2; PARP-2; ADPRTL2; ADPRTL3; pADPRT-2;
Gene ID
MIM
UniProt ID
Q9UGN5
Chromosome Location
14q11.2-q12
Pathway
BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Regulation of Telomerase, organism-specific biosystem;
Function
DNA binding; NAD+ ADP-ribosyltransferase activity; transferase activity, transferring glycosyl groups;
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------
Cat#
Product Name
Titer
Product Size
Species
Price
AD11827Z
>1x 10^9 vp/ml
1 x 0.2 ml
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CDCB175375
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