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Human FSHR Stable Cell Line-HEK293

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Cat.No.
CSC-RG0010
Background
Follicle stimulating hormone receptor belongs to a family of G-protein coupled receptors which activate adenylate cyclase. FSHR is a transmembrane receptor that interacts with the follicle stimulating hormone(FSH). In the ovary, the FSH receptor is necessary for follicular development and it is expressed on the granulosa cells. In the male, the FSH receptor has been identified on the Sertoli cells that are critical for spermatogenesis. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
FSHR
Synonyms
FSHR; follicle stimulating hormone receptor; ODG1; follicle-stimulating hormone receptor; FSHRO; LGR1; FSH receptor; follitropin receptor; MGC141667; MGC141668;
Gene ID
MIM
UniProt ID
P23945
Chromosome Location
2p21-p16
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Hormone ligand-binding receptors, organism-specific biosystem;
Function
follicle-stimulating hormone receptor activity; peptide hormone binding; protein binding; receptor activity; signal transducer activity;

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