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Siah1A

Official Full Name
siah E3 ubiquitin protein ligase 1A
Organism
Mus musculus
GeneID
20437
Background
Enables several functions, including disordered domain specific binding activity; protein homodimerization activity; and zinc ion binding activity. Involved in canonical Wnt signaling pathway and proteasome-mediated ubiquitin-dependent protein catabolic process. Acts upstream of or within several processes, including male meiosis I; regulation of growth; and spermatogenesis. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including alimentary system; early embryo; gonad; hemolymphoid system gland; and liver. Orthologous to human SIAH1 (siah E3 ubiquitin protein ligase 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Siah1a; Sinh1a;

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