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PPAT

Official Full Name
phosphoribosyl pyrophosphate amidotransferase
Organism
Homo sapiens
GeneID
5471
Background
The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq, Mar 2011]
Synonyms
GPAT; PRAT; ATASE;

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