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PDE6B


Official Full Name
phosphodiesterase 6B
Organism
Homo sapiens
Gene ID
5158
Background
Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Synonyms
rd1; PDEB; RP40; CSNB3; CSNBAD2; GMP-PDEbeta

Cat.No. Product Name Price
SHH372512 shRNA set against Human PDE6B (NM_000283.3) Inquiry
SHH372516 shRNA set against Mouse PDE6B (NM_008806.2) Inquiry
SHH372520 shRNA set against Rat PDE6B (NM_001106024.1) Inquiry
SHR100506 shRNA set against Mouse Pde6b(NM_008806.2) Inquiry
Cat.No. Product Name Price
CDFH013933 Human PDE6B cDNA Clone(NM_001145291.1) Inquiry
CDFH013934 Human PDE6B cDNA Clone(NM_001145292.1) Inquiry
CDFL010074 Mouse Pde6b cDNA Clone(NM_008806.2) Inquiry
CDFR005797 Rat Pde6b cDNA Clone(NM_001106024.1) Inquiry
MiUTR1M-09055 PDE6B miRNA 3'UTR clone Inquiry
MiUTR3H-02017 PDE6B miRNA 3'UTR clone Inquiry
MiUTR3H-02018 PDE6B miRNA 3'UTR clone Inquiry
MiUTR3H-02019 PDE6B miRNA 3'UTR clone Inquiry
CDCB159621 Human PDE6B ORF clone (BC000249) Inquiry
CDCL147459 Human PDE6B ORF clone (NM_001145291.1) Inquiry
CDCL147461 Human PDE6B ORF clone (NM_001145292.1) Inquiry
CDCL147467 Mouse Pde6b ORF clone (NM_008806.2) Inquiry
CDCR372826 Rat Pde6b ORF Clone(NM_001106024.1) Inquiry
CDCS405546 Human PDE6B ORF Clone (BC000249) Inquiry
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