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MEGF10

Official Full Name
multiple EGF like domains 10
Organism
Homo sapiens
GeneID
84466
Background
This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012]
Synonyms
SR-F3; EMARDD; CMYO10A; CMYO10B; CMYP10A; CMYP10B;

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