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Luciferase


Official Full Name
Luciferase
Synonyms
Luciferase; ec 1.13.12.7; Firefly; Luciferin 4 monooxygenase

Cat.No. Product Name Price
CSC-RR0224 Luc Reporter Cell Line-4T1 Inquiry
CSC-RR00830 Luciferase Reporter Cell Line - SIHA Inquiry
CSC-RR00833 Luciferase Reporter Cell Line - SK-MEL-1 Inquiry
CSC-RR00834 Luciferase Reporter Cell Line - SK-MEL-2 Inquiry
CSC-RR00836 Luciferase Reporter Cell Line - SK-N-SH Inquiry
CSC-RR00839 Luciferase Reporter Cell Line - SV-HUC-1 Inquiry
CSC-RR00842 Luciferase Reporter Cell Line - SW620 Inquiry
CSC-RR00843 Luciferase Reporter Cell Line - T98G Inquiry
CSC-RR00846 Luciferase Reporter Cell Line - TC-1 Inquiry
CSC-RR00847 Luciferase Reporter Cell Line - TE-1 Inquiry
CSC-RR00849 Luciferase Reporter Cell Line - TM4 Inquiry
CSC-RR00852 Luciferase Reporter Cell Line - U14 Inquiry
CSC-RR00855 Luciferase Reporter Cell Line - U266 Inquiry
CSC-RR00857 Luciferase Reporter Cell Line - UM-UC-3 Inquiry
CSC-RR00858 Luciferase Reporter Cell Line - WERI-Rb-1 Inquiry
CSC-RR00860 Luciferase Reporter Cell Line - Y1 Inquiry
CSC-RR00862 Luciferase Reporter Cell Line - ZJU-0430 Inquiry
CSC-RR00863 Luciferase Reporter Cell Line - ZR-75-1 Inquiry
CSC-RR00864 Luciferase Reporter Cell Line - AML-12 Inquiry
CSC-RR00924 Luciferase Reporter Cell Line - HEK293T Inquiry
CSC-RR00925 Luciferase Reporter Cell Line - MPC-5 Inquiry
CSC-RR00926 Luciferase Reporter Cell Line - Mac-T Inquiry
CSC-RR00927 Luciferase Reporter Cell Line - SW-13 Inquiry
CSC-RR00928 Luciferase Reporter Cell Line - Kupffer Inquiry
CSC-RR00929 Luciferase Reporter Cell Line - HEL Inquiry
CSC-RR00930 Luciferase Reporter Cell Line - MH-S Inquiry
CSC-RR00931 Luciferase Reporter Cell Line - SN4741 Inquiry
CSC-RR00932 Luciferase Reporter Cell Line - VSC4.1 Inquiry
CSC-RR00829 Luciferase Reporter Cell Line - SCC7 Inquiry
CSC-RR00827 Luciferase Reporter Cell Line - RWPE-1 Inquiry
CSC-RR00826 Luciferase Reporter Cell Line - Renca Inquiry
CSC-RR00824 Luciferase Reporter Cell Line - RBL-2H3 Inquiry
CSC-RR00773 Luciferase Reporter Cell Line - HEC-1-A Inquiry
CSC-RR00775 Luciferase Reporter Cell Line - HEC-1-B Inquiry
CSC-RR00777 Luciferase Reporter Cell Line - Hep 3B2.1-7 Inquiry
CSC-RR00780 Luciferase Reporter Cell Line - HNE1 Inquiry
CSC-RR00782 Luciferase Reporter Cell Line - HOS Inquiry
CSC-RR00783 Luciferase Reporter Cell Line - HPAF-II Inquiry
CSC-RR00784 Luciferase Reporter Cell Line - J82 Inquiry
CSC-RR00786 Luciferase Reporter Cell Line - K7M2-WT Inquiry
CSC-RR00787 Luciferase Reporter Cell Line - KTC-1 Inquiry
CSC-RR00789 Luciferase Reporter Cell Line - L1210 Inquiry
CSC-RR00791 Luciferase Reporter Cell Line - LOVO Inquiry
CSC-RR00795 Luciferase Reporter Cell Line - MADB106 Inquiry
CSC-RR00796 Luciferase Reporter Cell Line - MBT-2 Inquiry
CSC-RR00933 Luciferase Reporter Cell Line - LLC-PK1 Inquiry
CSC-RR00797 Luciferase Reporter Cell Line - MFC Inquiry
CSC-RR00800 Luciferase Reporter Cell Line - min6 Inquiry
CSC-RR00802 Luciferase Reporter Cell Line - MKN-74 Inquiry
CSC-RR00803 Luciferase Reporter Cell Line - MOVAS Inquiry
CSC-RR00805 Luciferase Reporter Cell Line - NCI-H292 Inquiry
CSC-RR00807 Luciferase Reporter Cell Line - NCI-H446 Inquiry
CSC-RR00809 Luciferase Reporter Cell Line - NCI-H661 Inquiry
CSC-RR00811 Luciferase Reporter Cell Line - NCI-H838 Inquiry
CSC-RR00812 Luciferase Reporter Cell Line - NCI-N87 Inquiry
CSC-RR00814 Luciferase Reporter Cell Line - NRK-52E Inquiry
CSC-RR00817 Luciferase Reporter Cell Line - OCM1A Inquiry
CSC-RR00818 Luciferase Reporter Cell Line - Panc 0813 Inquiry
CSC-RR00820 Luciferase Reporter Cell Line - PLC/PRF/5 Inquiry
CSC-RR00821 Luciferase Reporter Cell Line - Py230 Inquiry
CSC-RR00799 Luciferase Reporter Cell Line - MHCC97-L Inquiry
CSC-RR00772 Luciferase Reporter Cell Line - HCT-8 Inquiry
CSC-RR00934 Luciferase Reporter Cell Line - MOC2 Inquiry
CSC-RR00936 Luciferase Reporter Cell Line - SGC-7911 Inquiry
CSC-RR00971 Luciferase Reporter Cell Line - SNU398 Inquiry
CSC-RR00972 Luciferase Reporter Cell Line - DU145 Inquiry
CSC-RR01178 Luciferase Reporter Cell Line - 95-D Inquiry
CSC-RR01180 Luciferase Reporter Cell Line - AKR Inquiry
CSC-RR01182 Luciferase Reporter Cell Line - BIU-87 Inquiry
CSC-RR01183 Luciferase Reporter Cell Line - C666-1 Inquiry
CSC-RR01197 Luciferase Reporter Cell Line - HuCCT1 Inquiry
CSC-RR01201 Luciferase Reporter Cell Line - KLN205 Inquiry
CSC-RR01209 Luciferase Reporter Cell Line - McA-RH7777 Inquiry
CSC-RR01212 Luciferase Reporter Cell Line - MG63 Inquiry
CSC-RR01214 Luciferase Reporter Cell Line - MKN7 Inquiry
CSC-RR01218 Luciferase Reporter Cell Line - MSC Inquiry
CSC-RR01219 Luciferase Reporter Cell Line - MUM-2B Inquiry
CSC-RR01220 Luciferase Reporter Cell Line - MyC-CaP Inquiry
CSC-RR01222 Luciferase Reporter Cell Line - NCI-H1703 Inquiry
CSC-RR01223 Luciferase Reporter Cell Line - NCI-H226 Inquiry
CSC-RR01227 Luciferase Reporter Cell Line - OVCAR3 Inquiry
CSC-RR01230 Luciferase Reporter Cell Line - RD Inquiry
CSC-RR01233 Luciferase Reporter Cell Line - SBC-5 Inquiry
CSC-RR01236 Luciferase Reporter Cell Line - SN12-PM6 Inquiry
CSC-RR01237 Luciferase Reporter Cell Line - T47D Inquiry
CSC-RR01238 Luciferase Reporter Cell Line - TU686 Inquiry
CSC-RR01241 Luciferase Reporter Cell Line - U251MG/TMZ Inquiry
CSC-RR01263 Luciferase Reporter Cell Line - NCI-H69 Inquiry
CSC-RR01264 Luciferase Reporter Cell Line - COLO205 Inquiry
CSC-RR01276 Luc Reporter Cell Line - SW48 Inquiry
CSC-RR01277 Luc Reporter Cell Line - TPC-1 Inquiry
CSC-RR00970 Luciferase Reporter Cell Line - S2 Inquiry
CSC-RR00969 Luciferase Reporter Cell Line - RIN-m5F Inquiry
CSC-RR00968 Luciferase Reporter Cell Line - R28 Inquiry
CSC-RR00967 Luciferase Reporter Cell Line - NCI-H929 Inquiry
CSC-RR00937 Luciferase Reporter Cell Line - V79 Inquiry
CSC-RR00938 Luciferase Reporter Cell Line - IBMDM Inquiry
CSC-RR00939 Luciferase Reporter Cell Line - SNT-8 Inquiry
CSC-RR00940 Luciferase Reporter Cell Line - SP2/0-AG14 Inquiry
CSC-RR00941 Luciferase Reporter Cell Line - SCC-25 Inquiry
CSC-RR00942 Luciferase Reporter Cell Line - 2v6.11 Inquiry
CSC-RR00943 Luciferase Reporter Cell Line - 293t/17 Inquiry
CSC-RR00944 Luciferase Reporter Cell Line - DC2.4 Inquiry
CSC-RR00945 Luciferase Reporter Cell Line - AR42J Inquiry
CSC-RR00947 Luciferase Reporter Cell Line - HEPG2-C3A Inquiry
CSC-RR00948 Luciferase Reporter Cell Line - RPE1 (hTERT, p53-/-) Inquiry
CSC-RR00949 Luciferase Reporter Cell Line - CAL-33 Inquiry
CSC-RR00950 Luciferase Reporter Cell Line - RSC96 Inquiry
CSC-RR00935 Luciferase Reporter Cell Line - MDBK Inquiry
CSC-RR00952 Luciferase Reporter Cell Line - NCI-H716 Inquiry
CSC-RR00954 Luciferase Reporter Cell Line - HLE-B3 Inquiry
CSC-RR00955 Luciferase Reporter Cell Line - 3T3-L1 Inquiry
CSC-RR00956 Luciferase Reporter Cell Line - NRK-49F Inquiry
CSC-RR00957 Luciferase Reporter Cell Line - VCAP Inquiry
CSC-RR00958 Luciferase Reporter Cell Line - BHK21(C-13) Inquiry
CSC-RR00959 Luciferase Reporter Cell Line - Calu-3 Inquiry
CSC-RR00960 Luciferase Reporter Cell Line - GT1-7 Inquiry
CSC-RR00961 Luciferase Reporter Cell Line - HMRSV5 Inquiry
CSC-RR00962 Luciferase Reporter Cell Line - INS-1 Inquiry
CSC-RR00963 Luciferase Reporter Cell Line - KMRC-1 Inquiry
CSC-RR00964 Luciferase Reporter Cell Line - LNCaP Inquiry
CSC-RR00965 Luciferase Reporter Cell Line - MC3T3-E1 Inquiry
CSC-RR00966 Luciferase Reporter Cell Line - NCI-H3122 Inquiry
CSC-RR00953 Luciferase Reporter Cell Line - KMS-12-PE Inquiry
CSC-RR00770 Luciferase Reporter Cell Line - HCCLM3 Inquiry
CSC-RR00768 Luciferase Reporter Cell Line - HCC1806 Inquiry
CSC-RR00767 Luciferase Reporter Cell Line - hacat Inquiry
CSC-RR00622 Luciferase Reporter Cell Line - WEHI-3 Inquiry
CSC-RR00626 Luciferase Reporter Cell Line - PANC-1 Inquiry
CSC-RR00627 Luciferase Reporter Cell Line - BPH-1 Inquiry
CSC-RR00629 Luciferase Reporter Cell Line - ARPE-19 Inquiry
CSC-RR00653 Luciferase Reporter Cell Line - 5637 Inquiry
CSC-RR00654 Luciferase Reporter Cell Line - 22RV1 Inquiry
CSC-RR00655 Luciferase Reporter Cell Line - 266-6 Inquiry
CSC-RR00656 Luciferase Reporter Cell Line - 293T Inquiry
CSC-RR00657 Luciferase Reporter Cell Line - 3D4/21 Inquiry
CSC-RR00658 Luciferase Reporter Cell Line - A-431 Inquiry
CSC-RR00659 Luciferase Reporter Cell Line - ACHN Inquiry
CSC-RR00660 Luciferase Reporter Cell Line - AGS Inquiry
CSC-RR00661 Luciferase Reporter Cell Line - ATDC5 Inquiry
CSC-RR00662 Luciferase Reporter Cell Line - BAF3 Inquiry
CSC-RR00663 Luciferase Reporter Cell Line - BEAS-2B Inquiry
CSC-RR00664 Luciferase Reporter Cell Line - BeWo Inquiry
CSC-RR00665 Luciferase Reporter Cell Line - BJ Inquiry
CSC-RR00666 Luciferase Reporter Cell Line - BV2 Inquiry
CSC-RR00667 Luciferase Reporter Cell Line - C2C12 Inquiry
CSC-RR00668 Luciferase Reporter Cell Line - C3A Inquiry
CSC-RR00669 Luciferase Reporter Cell Line - Caco-2 Inquiry
CSC-RR00670 Luciferase Reporter Cell Line - Caov-3 Inquiry
CSC-RR00671 Luciferase Reporter Cell Line - CHO-K1 Inquiry
CSC-RR00672 Luciferase Reporter Cell Line - EO771 Inquiry
CSC-RR00673 Luciferase Reporter Cell Line - EA.hy926 Inquiry
CSC-RR00674 Luciferase Reporter Cell Line - H9c2(2-1) Inquiry
CSC-RR00675 Luciferase Reporter Cell Line - HCC827 Inquiry
CSC-RR0609M Luc Reporter Cell Line - GL261 Inquiry
CSC-RR0631 Luciferase Reporter Cell Line - LL/2 (LLC1) Inquiry
CSC-RR0630 Luciferase Reporter Cell Line - KPC Inquiry
CSC-RR0629 Luciferase Reporter Cell Line - JC Inquiry
CSC-RR0234 Luc Reporter Cell Line-B16F10 Inquiry
CSC-RR0237 Luc Reporter Cell Line-CT26 Inquiry
CSC-RR0245 Luc Reporter Cell Line - LL/2 (LLC1) Inquiry
CSC-RR0288 NFkB-Luc Reporter Cell Line - RAW 264.7 Inquiry
CSC-RR0290 CXCL2-Luc Reporter Cell Line - RAW 264.7 Inquiry
CSC-RR0292 TNFα-Luc Reporter Cell Line - RAW 264.7 Inquiry
CSC-RR0294 TNFβ-Luc Reporter Cell Line - RAW 264.7 Inquiry
CSC-RR0296 NFAT-Luc Reporter Cell Line - RAW 264.7 Inquiry
CSC-RR0297 STAT1-Luc Reporter Cell Line - RAW 264.7 Inquiry
CSC-RR0299 iNOS-Luc Reporter Cell Line - RAW 264.7 Inquiry
CSC-RR0300 IL6-Luc Reporter Cell Line-NIH3T3 Inquiry
CSC-RR0312 STAT5-Luc Reporter Cell Line-Ba/F3 Inquiry
CSC-RR0364 Luciferase Reporter Cell Line - Hepa1-6 Inquiry
CSC-RR00676 Luciferase Reporter Cell Line - HGC-27 Inquiry
CSC-RR0369 Luciferase Reporter Cell Line - C1498 Inquiry
CSC-RR0376 Luciferase Reporter Cell Line - NIH/3T3 Inquiry
CSC-RR0385 NFkB Luciferase Reporter Cell Line - MEF Inquiry
CSC-RR0386 NFkB Luciferase Reporter Cell Line - Neuro2a Inquiry
CSC-RR0388 NFAT Luciferase Reporter Cell Line - NIH/3T3 Inquiry
CSC-RR0393 NRF2/ARE Luciferase Reporter Cell Line - NIH/3T3 Inquiry
CSC-RR0395 HIF Luciferase Reporter Cell Line - Neuro2a Inquiry
CSC-RR0400 CREB Luciferase Reporter Cell Line - NIH/3T3 Inquiry
CSC-RR0494 Luciferase Reporter Cell Line - MC38 Inquiry
CSC-RR0547 Luciferase Reporter Cell Line - Neuro2a Inquiry
CSC-RR0604 Luciferase Reporter Cell Line - Panc02 Inquiry
CSC-RR0619 Luciferase Reporter Cell Line - EMT6 Inquiry
CSC-RR0621 Luciferase Reporter Cell Line - H22 Inquiry
CSC-RR0625 Luciferase Reporter Cell Line - HPTGER2 Inquiry
CSC-RR0370 Luciferase Reporter Cell Line - A20 Inquiry
CSC-RR00677 Luciferase Reporter Cell Line - HK-1 Inquiry
CSC-RR00678 Luciferase Reporter Cell Line - HL-1 Inquiry
CSC-RR00679 Luciferase Reporter Cell Line - HSC3 Inquiry
CSC-RR00715 Luciferase Reporter Cell Line - SNU-387 Inquiry
CSC-RR00716 Luciferase Reporter Cell Line - SW 1353 Inquiry
CSC-RR00717 Luciferase Reporter Cell Line - T24 Inquiry
CSC-RR00718 Luciferase Reporter Cell Line - TM3 Inquiry
CSC-RR00719 Luciferase Reporter Cell Line - U251MG Inquiry
CSC-RR00720 Luciferase Reporter Cell Line - U-2932 Inquiry
CSC-RR00721 Luciferase Reporter Cell Line - Vero Inquiry
CSC-RR00722 Luciferase Reporter Cell Line - VERO C1008 (E6) Inquiry
CSC-RR00730 Luciferase Reporter Cell Line - 143B Inquiry
CSC-RR00732 Luciferase Reporter Cell Line - 5-8F Inquiry
CSC-RR00733 Luciferase Reporter Cell Line - A2780 Inquiry
CSC-RR00736 Luciferase Reporter Cell Line - AsPC-1 Inquiry
CSC-RR00737 Luciferase Reporter Cell Line - Bcpap Inquiry
CSC-RR00714 Luciferase Reporter Cell Line - SK-MES-1 Inquiry
CSC-RR00738 Luciferase Reporter Cell Line - bEnd.3 Inquiry
CSC-RR00742 Luciferase Reporter Cell Line - BT474 Inquiry
CSC-RR00743 Luciferase Reporter Cell Line - Caki-2 Inquiry
CSC-RR00745 Luciferase Reporter Cell Line - CAL 27 Inquiry
CSC-RR00747 Luciferase Reporter Cell Line - Capan-2 Inquiry
CSC-RR00749 Luciferase Reporter Cell Line - CFPAC-1 Inquiry
CSC-RR00750 Luciferase Reporter Cell Line - CNE-2Z Inquiry
CSC-RR00752 Luciferase Reporter Cell Line - cos-1 Inquiry
CSC-RR00754 Luciferase Reporter Cell Line - Daoy Inquiry
CSC-RR00755 Luciferase Reporter Cell Line - DLD-1 Inquiry
CSC-RR00758 Luciferase Reporter Cell Line - EJ-1 Inquiry
CSC-RR00760 Luciferase Reporter Cell Line - FAdu Inquiry
CSC-RR00761 Luciferase Reporter Cell Line - G422 Inquiry
CSC-RR00764 Luciferase Reporter Cell Line - GH3 Inquiry
CSC-RR00740 Luciferase Reporter Cell Line - BRL Inquiry
CSC-RR01279 Luc Reporter Cell Line - ES-2 Inquiry
CSC-RR00713 Luciferase Reporter Cell Line - SK-HEP-1 Inquiry
CSC-RR00711 Luciferase Reporter Cell Line - SH-SY5Y Inquiry
CSC-RR00680 Luciferase Reporter Cell Line - HT-22 Inquiry
CSC-RR00681 Luciferase Reporter Cell Line - IPEC-J2 Inquiry
CSC-RR00682 Luciferase Reporter Cell Line - ISHIKAWA Inquiry
CSC-RR00683 Luciferase Reporter Cell Line - JIMT-1 Inquiry
CSC-RR00684 Luciferase Reporter Cell Line - Jurkat, Clone E6-1 Inquiry
CSC-RR00685 Luciferase Reporter Cell Line - KGN Inquiry
CSC-RR00686 Luciferase Reporter Cell Line - KYSE-150 Inquiry
CSC-RR00687 Luciferase Reporter Cell Line - KYSE-30 Inquiry
CSC-RR00688 Luciferase Reporter Cell Line - L-929 Inquiry
CSC-RR00689 Luciferase Reporter Cell Line - LS 174T Inquiry
CSC-RR00691 Luciferase Reporter Cell Line - MC3T3-E1 Subclone 14 Inquiry
CSC-RR00694 Luciferase Reporter Cell Line - MDCK(NBL-2) Inquiry
CSC-RR00695 Luciferase Reporter Cell Line - MFE-280 Inquiry
CSC-RR00712 Luciferase Reporter Cell Line - SK-BR-3 Inquiry
CSC-RR00696 Luciferase Reporter Cell Line - MGC803 Inquiry
CSC-RR00698 Luciferase Reporter Cell Line - MLO-Y4 Inquiry
CSC-RR00699 Luciferase Reporter Cell Line - NCI-H520 Inquiry
CSC-RR00700 Luciferase Reporter Cell Line - NIT-1 Inquiry
CSC-RR00701 Luciferase Reporter Cell Line - Nthy-ori 3-1 Inquiry
CSC-RR00702 Luciferase Reporter Cell Line - OVCAR-3 Inquiry
CSC-RR00703 Luciferase Reporter Cell Line - PC-12 Inquiry
CSC-RR00704 Luciferase Reporter Cell Line - PC-3 Inquiry
CSC-RR00705 Luciferase Reporter Cell Line - PC-3M Inquiry
CSC-RR00706 Luciferase Reporter Cell Line - RAW 264.7 Inquiry
CSC-RR00707 Luciferase Reporter Cell Line - RKO Inquiry
CSC-RR00708 Luciferase Reporter Cell Line - RM-1 Inquiry
CSC-RR00709 Luciferase Reporter Cell Line - SACC-LM Inquiry
CSC-RR00710 Luciferase Reporter Cell Line - Saos-2 Inquiry
CSC-RR00697 Luciferase Reporter Cell Line - MHCC97-H Inquiry
CSC-RR01282 Luc Reporter Cell Line - C6 Inquiry

Detailed Information

The phenomenon of bioluminescence has been observed in many different organisms including bacteria, fungi, algae, fish, squid, shrimp and insects. Luminous organisms produce light by an enzymatic reaction of a luciferase (=enzyme) with a luciferin (=substrate). Light-emitting reactions are quite distinct among luminous organisms, but in each case, the reaction is an oxidation process with molecular oxygen and is a conversion of chemical energy into light. The various luciferase genes have been isolated and adapted as reporter genes. Firefly luciferase (FLuc) has been studied for the last 50 years and proven to be a useful enzyme. It has been widely used in molecular and cell biology, particularly for the quantification of ATP and as a reporter enzyme of gene expression.

One of the main reasons for the widespread use of luciferase in bioassays is that, unlike fluorescence, luminescence does not require excitation light energy, so lowering the background signal to provide a sensitive assay with a high signal-to-background ratio. Elimination of an excitation light source also prevents interference by compound fluorescence and fluorophore photobleaching. Thus, luminescence assays can be very sensitive, despite significantly weaker signal intensity than fluorescence. For cell-based assays, the use of FLuc or Renilla luciferase (RLuc) enzymes as reporters enable the measurement of dynamic changes in reporter transcription levels because the intracellular protein half-lives of these luciferase enzymes are relatively short compared to nonenzymatic fluorescent protein reporters (e.g., GFP).

Principle of a simple luciferase reporter assay.Figure 1. Principle of a simple luciferase reporter assay.

Gene function analysis, target discovery and validation, compound screening, and assay development often need cell-based assays. Stable cell lines that are engineered to express a gene of interest by transgene integrations into the host genome provide an efficient approach to conduct such analysis. Creative Biogene can help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions. We offer a wide-selection of validated luciferase reporter cell lines that measure transcription factor activity as a read-out for various signaling pathways.

Features:

  • Consistent - TF reporter construct is stably integrated into the genome to avoid experimental/cell-to-cell variations.
  • High sensitive and responsive - Each cell line is validated to induce strong reporter signal in response to stimuli.
  • Routine mycoplasma testing - All cell lines tested negative for mycoplasma.
  • Time saving - Cell line can be used for experiments right away to study different signaling pathways.
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