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IRGM1

Official Full Name
immunity related GTPase M
Organism
Homo sapiens
GeneID
345611
Background
This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
Synonyms
IRGM; IFI1; IBD19; IRGM1; LRG47; LRG-47;

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