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Hsd3B5

Official Full Name
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
Organism
Mus musculus
GeneID
15496
Background
Predicted to enable 3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity; steroid binding activity; and steroid delta-isomerase activity. Involved in response to stilbenoid. Located in mitochondrial inner membrane. Is expressed in several structures, including adrenal gland; genitourinary system; gut; liver and biliary system; and spleen. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Hsd3b5;

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