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her5

Official Full Name
hairy-related 5
Organism
Danio rerio
GeneID
30285
Background
Enables protein heterodimerization activity and protein homodimerization activity. Acts upstream of or within several processes, including midbrain-hindbrain boundary development; negative regulation of neurogenesis; and positive regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to be active in nucleus. Is expressed in several structures, including EVL; brain; endoderm; neural plate; and presumptive structure. Human ortholog(s) of this gene implicated in spondylocostal dysostosis 4. Orthologous to human HES7 (hes family bHLH transcription factor 7). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
her-5; zgc:136537;

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